An update on first line therapies for metastatic breast cancer

Palma Fedele

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An update on first line therapies for metastatic breast cancer

机译：转移性乳腺癌第一线疗法的更新

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Introduction: In recent years, outcomes of patients with metastatic breast cancer (MBC) have improved due to a greater understanding of the mechanisms of carcinogenesis in the development of newer molecularly targeted drugs, especially those as a front-line therapy. Remarkable improvements have been made in the treatment of hormone receptor positive (HR+) and Her2 positive MBC and currently targeted treatment strategies represent a valid first line treatment.

机译：介绍：近年来，由于对新分子靶向药物的发展中的致癌机制，尤其是作为前线治疗的致癌机制，转移性乳腺癌患者（MBC）的结果提高了改善。在激素受体阳性（HR +）和HER2阳性MBC和目前有针对性的治疗策略方面取得了显着的改善，代表了有效的第一线治疗方法。

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来源
《Expert opinion on pharmacotherapy》 |2018年第6期|共10页
作者
Palma Fedele;
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作者单位

Medical Oncology &

Breast Unit ‘Antonio Perrino’ Hospital Brindisi Italy;

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原文格式 PDF
正文语种 eng
中图分类药学;
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专利

1. 单克隆抗体Herceptin免疫疗法治疗乳腺癌--在治疗转移性乳腺癌方面的新进展 [J] . 管敬东, 乔福元, 胡国清中德临床肿瘤学杂志（英文版） . 2001,第003期
2. 440 Superiority of tandem high-dose (HDC) over conventionally-dosed chemotherapy(CDC) in patients (Pts) with metastatic breast cancer (MBC): Updated results of the international randomised breast cancer dose-intensity study (IBDIS) [J] . J.Crown, S.Leyvraz, M.Verrill, European Journal of Cancer Supplements . 2003,第5期

机译：440在转移性乳腺癌（MBC）患者（Pts）中，串联大剂量（HDC）优于常规剂量化疗（CDC）：国际随机乳腺癌剂量强度研究（IBDIS）的更新结果
3. Update 2010 of the German AGO Recommendations for the Diagnosis and Treatment of Early and Metastatic Breast Cancer - Chapter A: Surgery, Pathology and Prognostic Factors, Adjuvant and Neoadjuvant Therapy, Adjuvant Radiotherapy [J] . Christoph Thomssen, Nadia Harbeck, on behalf of the AGO Breast Committee Breast care . 2010,第4期

机译：德国AGO关于早期和转移性乳腺癌的诊断和治疗建议的2010年更新-A章：手术，病理和预后因素，辅助和新辅助治疗，辅助放疗
4. Update 2010 of the German AGO Recommendations for the Diagnosis and Treatment of Early and Metastatic Breast Cancer - Chapter A: Surgery, Pathology and Prognostic Factors, Adjuvant and Neoadjuvant Therapy, Adjuvant Radiotherapy [J] . Christoph Thomssena, Nadia Harbeckb Breast care . 2010,第4期

机译：德国AGO关于诊断和治疗早期和转移性乳腺癌的建议的2010年更新-A章：手术，病理和预后因素，辅助和新辅助治疗，辅助放疗
5. Multifunctional ECO-mediated delivery of miR-200b for metastatic breast cancer therapy [C] . Nadia Ayat, Laura Hertz, Amita M Vaidya, World biomaterials congress . 2016

机译：多功能ECO介导的miR-200b用于转移性乳腺癌治疗
6. Investigating age varying effect of access to cancer care on immediate choice of chemotherapy among elderly women with metastatic breast cancer. [D] . Wan, Shaowei. 2010

机译：调查在转移性乳腺癌的老年妇女中，癌症治疗对立即选择化疗的年龄差异影响。
7. Update 2010 of the German AGO Recommendations for the Diagnosis and Treatment of Early and Metastatic Breast Cancer - Chapter A: Surgery Pathology and Prognostic Factors Adjuvant and Neoadjuvant Therapy Adjuvant Radiotherapy [O] . Christoph Thomssena, Nadia Harbeckb 2010

机译：2010年德国AGO关于早期和转移性乳腺癌的诊断和治疗建议的最新动态-A章：手术病理学和预后因素辅助和新辅助治疗辅助放疗
8. Update 2010 of the German AGO Recommendations for the Diagnosis and Treatment of Early and Metastatic Breast Cancer - Chapter A: Surgery, Pathology and Prognostic Factors, Adjuvant and Neoadjuvant Therapy, Adjuvant Radiotherapy [O] . Thomssena, Christoph, Harbeckb, Nadia 2010

机译：2010年德国AGO关于早期和转移性乳腺癌的诊断和治疗建议的最新动态-A章：手术，病理学和预后因素，辅助和新辅助治疗，辅助放疗
9. Novel Differentiation Therapy Approach to Reduce the Metastatic Potential of Basal, Highly Metastatic, Triple-Negative Breast Cancers. [R] . Chu, I. 2012

机译：新型分化治疗方法降低基底，高转移性，三阴性乳腺癌的转移潜能。

An update on first line therapies for metastatic breast cancer

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