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Breastfeeding duration and the risk of coronary artery disease

机译:母乳喂养持续时间和冠状动脉疾病的风险

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摘要

Badigtoyndh Previous studies have suggested that prolonged breastfeeding has beneficial effects on the health of the mother including the reduction of long-term risk of coronary artery disease (CAD). The mechanism of this association remains unclear. Methods; We surveyed 643 women aged 40-65 years receiving outpatient care at Stanford University Hospital on their reproductive/lactation history, including 137 women (cases) with clinically confirmed CAD. Survey data were supplemented with traditional risk factor data for CAD obtained from the participant's medical record. We then conducted logistic regression analyses to assess the relationship between breastfeeding duration and case- control status for each of the two separate definitions of duration. The first was based on the participant's single longest duration of breastfeeding considering all live births reported and the second was based on a participant's total duration of breastfeeding summed over all live births. For each of these two definitions, we ran three sequential models each with a different reference group nulliparous women, (2) parous women that never breastfed, and (3) parous women with a short duration of breastfeeding — successively excluding women in the reference group of the previous model(s).
机译:Badigtoyndh上一项研究表明,长期的母乳喂养对母亲的健康有益的影响,包括减少冠状动脉疾病的长期风险(CAD)。这种关联的机制尚不清楚。方法;在斯坦福大学医院接受了40-65岁的643名妇女对他们的生殖/哺乳期历史,其中有137名妇女(病例),临床证实的CAD。调查数据辅以从参与者的病历中获得的CAD的传统风险因素数据。然后,我们进行了逻辑回归分析,以评估母乳喂养持续时间和案例控制状态之间的关系,每个单独定义的持续时间中的每一个。首先是基于参与者的单一母乳喂养母乳喂养,考虑所有报告的所有活产出生,第二个是基于参与者在所有活产出生的总母乳喂养的总母乳喂养持续时间。对于这两种定义中的每一个,我们每次运行三种顺序模型,其中包含不同的参考组无损失女性,(2)寄生妇女从未母乳喂养,(3)持久母乳喂养的持久性妇女 - 先后除了母乳喂养以前的模型。

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