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Antibacterial effects of silver incorporated zeolite coatings on 3D printed porous stainless steels

机译:3D印刷多孔不锈钢上银掺入沸石涂层的抗菌作用

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Functionalization of porous metals with antibacterial coatings is hotly pursued in recent decade. Here we fabricated a highly porous stainless steel component by selective laser melting and then coated with silver incorporated zeolite by in situ hydrothermal crystallization method. The morphology of their surface was investigated by scanning electron microscopy. The inhibition of Escherichia coil and Staphylococcus aureus were identified by bacterial viability studies after 24 h of incubation. More importantly, the obtained coatings show better osteointegration by spreading bone marrow stromal cells (BMSCs) after cultured with different scaffold extract solutions for 1, 3, and 5 days. These results suggest that silver incorporated zeolite coatings on 3D printed porous stainless steels exhibit better antibacterial activity and biocompatibility, showing potential application in the field of medical implant materials.
机译:近十年来,热追求多孔金属与抗菌涂料的官能化。 在这里,我们通过选择性激光熔化制造了高度多孔的不锈钢组分,然后通过原位水热结晶法涂覆银掺入沸石。 通过扫描电子显微镜研究其表面的形态。 通过在孵育24小时后通过细菌活力研究鉴定对大肠杆菌线圈和金黄色葡萄球菌的抑制。 更重要的是,所获得的涂层通过在用不同支架提取溶液培养1,3和5天之后通过展开骨髓基质细胞(BMSC)而更好地显示出更好的骨囊肿。 这些结果表明,3D印刷多孔不锈钢上的银掺入沸石涂层表现出更好的抗菌活性和生物相容性,显示出在医学植入物材料领域的潜在应用。

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