• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Nutrition >Effects of a novel therapeutic diet on liver enzymes and coagulating factors in patients with non-alcoholic fatty liver disease: A parallel randomized trial
【24h】

Effects of a novel therapeutic diet on liver enzymes and coagulating factors in patients with non-alcoholic fatty liver disease: A parallel randomized trial

机译：新型治疗饮食对非酒精性脂肪肝病患者肝酶及凝血因子的影响：平行随机试验

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Objective: There are several reports regarding the role of therapeutic diets for patients with non-alcoholic fatty liver disease (NAFLD). Therefore, the aim of this study was to determine the effects of a low-calorie, low-carbohydrate soy-containing diet on lipid profiles, liver enzymes, and coagulating factors in patients with NAFLD. Method: This was a randomized parallel clinical trial involving 45 patients with NAFLD. The participants consumed three kinds of diets for 8wk. Patients were randomly assigned to consume a low-calorie diet; a low-calorie, low-carbohydrate diet; or a low-calorie, low-carbohydrate soy-containing diet. Measurements were done according to the standard method. Results: Changes in weight were not significantly different in the three groups. The low-calorie, low-carbohydrate soy-containing diet could reduce alanine aminotransferase (-15.2±12.1 versus -6.8±4.6 in the low-calorie, low-carbohydrate diet, and -6.4±4.4 IU/L in the low-calorie diet; P=0.02) and serum fibrinogen levels (-49.1±60.1 versus -12.9±8.1 and -17.4±8.4g/L, respectively; P=0.01). Reductions in aspartate aminotransferase were significantly higher in the low-calorie, low-carbohydrate soy-containing group. Changes in lipid profiles did not differ significantly between the groups. The soy-containing diet did reduce malondialdehyde more than the other diets (P=0.01). Conclusion: A low-calorie, low-carbohydrate soy-containing diet could have beneficial effects on liver enzymes, malondialdehyde, and serum fibrinogen levels in patients with NAFLD.
机译：目的：有几条关于治疗性饮食对非酒精性脂肪肝病（NAFLD）的作用的报道。因此，本研究的目的是确定含低热量，含低碳水化合物大豆饮食的脂质谱，肝酶和NAFLD患者凝血因子的影响。方法：这是一项随机平行的临床试验，涉及45例NAFLD患者。参与者消耗了8wk的三种饮食。患者随机分配到消耗低卡路里的饮食;低卡路里，低碳水化合物饮食;或低卡路里，低碳水化合物含豆油饮食。根据标准方法进行测量。结果：三组重量的变化没有显着差异。低卡路里，低碳水化合物大豆饮食可以减少丙氨酸氨基转移酶（在低热量，低碳水化合物饮食中的丙氨酸氨基转移酶（-15.2±12.1对-6.8±4.6），低卡路里的-6.4±4.4 IU / L饮食; p = 0.02）和血清纤维蛋白原水平（-49.1±60.1与-12.9±8.1和-17.4±8.4g / l; p = 0.01）。低热量，含低碳水化合物大豆基团的天冬氨酸氨基转移酶减少显着高。脂质曲线的变化在组之间没有显着差异。含大豆的饮食确实比其他饮食更多地减少丙二醛（P = 0.01）。结论：低卡路里，含低碳水化合物大豆饮食可对NAFLD患者肝酶，丙二醛和血清纤维蛋白原水平具有有益作用。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号