SPACE - A randomized study of SBRT vs conventional fractionated radiotherapy in medically inoperable stage I NSCLC

Nyman Jan; Hallqvist Andreas; Lund Jo-Asmund; Brustugun Odd-Terje; Bergman Bengt; Bergstrom Per; Friesland Signe; Lewensohn Rolf; Holmberg Erik; Lax Ingmar

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SPACE - A randomized study of SBRT vs conventional fractionated radiotherapy in medically inoperable stage I NSCLC

机译：空间 - 在医学阶段I NSCLC中的SBRT与常规分级放射治疗的随机研究

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Background: Stereotactic body radiotherapy (SBRT) has been introduced for small lung tumors due to excellent local control and few side effects, even though there are no comparative studies. SPACE (Stereotactic Precision And Conventional radiotherapy Evaluation) is the first randomized phase II trial comparing SBRT and conventional fractionated radiotherapy (3DCRT).

机译：背景：由于局部控制优异的局部控制和少数副作用，已经为小肺肿瘤引入了立体定向体放射疗法，即使没有比较研究。空间（立体定位精度和常规放射疗法评估）是第一个随机化期II试验比较SBRT和常规分级放疗（3DCRT）。

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《Radiotherapy and oncology: Journal of the European Society for Therapeutic Radiology and Oncology》 |2016年第1期|共8页
作者
Nyman Jan; Hallqvist Andreas; Lund Jo-Asmund; Brustugun Odd-Terje; Bergman Bengt; Bergstrom Per; Friesland Signe; Lewensohn Rolf; Holmberg Erik; Lax Ingmar;
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作者单位

Sahlgrens Univ Hosp Gothenburg Sweden;

Sahlgrens Univ Hosp Gothenburg Sweden;

Trondheim Reg &

Univ Hosp Trondheim Norway;

Oslo Univ Hosp Oslo Norway;

Sahlgrens Univ Hosp Gothenburg Sweden;

Norrlands Univ Hosp Umea Sweden;

Karolinska Univ Hosp Stockholm Sweden;

Karolinska Univ Hosp Stockholm Sweden;

Sahlgrens Univ Hosp Gothenburg Sweden;

Karolinska Univ Hosp Stockholm Sweden;

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原文格式 PDF
正文语种 eng
中图分类肿瘤学;
关键词
SBRT; SABR; NSCLC; Stage I; Medically inoperable; Randomized;

机译：sbrt;sabr;nsclc;阶段我;医学上不可操作;随机;

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专利

1. SPACE - A randomized study of SBRT vs conventional fractionated radiotherapy in medically inoperable stage I NSCLC [J] . Nyman Jan, Hallqvist Andreas, Lund Jo-Asmund, Radiotherapy and oncology: Journal of the European Society for Therapeutic Radiology and Oncology . 2016,第1期

机译：SPACE-在医学上不能手术的I期非小细胞肺癌中SBRT与常规分次放疗的随机研究
2. A randomized Phase III trial of comparing two dose-fractionations stereotactic body radiotherapy (SBRT) for medically inoperable Stage IA non-small cell lung cancer or small lung lesions clinically diagnosed as primary lung cancer: Japan Clinical Oncology Group Study JCOG1408 (J-SBRT trial) [J] . Kimura Tomoki, Nagata Yasushi, Eba Junko, Japanese journal of clinical oncology. . 2017,第3期

机译：用于比较两种剂量分数立体定向体放射疗法（SBRT）的随机期III试验，用于医学上不可操作的阶段IA非小细胞肺癌或小肺病变临床诊断为原发性肺癌：日本临床肿瘤学群体学习JCOG1408（J-SBRT试验的）
3. Stereotactic precision and conventional radiotherapy evaluation (SPACE)-Trial for medically inoperable Stage I NSCLC: A lost opportunity? [J] . Alongi Filippo, Tebano Umberto, Mazzola Rosario Radiotherapy and oncology: Journal of the European Society for Therapeutic Radiology and Oncology . 2017,第2期

机译：立体定向和常规放射治疗评估（空间）用于医学上不可操作的阶段I NSCLC：失去机会？
4. Potential dosimetric benefit of dose-warping based 4D planning compared to conventional 3D planning in liver stereotactic body radiotherapy (SBRT) [C] . UJ Yeo, ML Taylor, T Kron, International Conference on 3D Radiation Dosimetry . 2013

机译：与肝脏立体定向体放射治疗中的常规3D规划相比，基于剂量翘曲的4D规划的潜在剂量效益（SBRT）
5. A Randomized Clinical Split Mouth Study Comparing Conventional Techniques to Lasers for Second Stage Implant Uncovering. [D] . Rossi, Andrew M., Jr. 2014

机译：一项将常规技术与第二阶段植入物暴露的激光进行比较的随机临床裂口研究。
6. NRG Oncology RTOG 0915 (NCCTG N0927): A Randomized Phase II Study Comparing 2 Stereotactic Body Radiation Therapy (SBRT) Schedules for Medically Inoperable Patients with Stage I Peripheral Non-Small Cell Lung Cancer [O] . Gregory M. M. Videtic, Chen Hu, Anurag K. Singh, -1

机译：NRG肿瘤学RTOG 0915（NCCTG N0927）：一项随机II期研究比较2种立体定向放射治疗（SBRT）方案用于不能手术治疗的I期外周非小细胞肺癌患者
7. A randomized Phase III trial of comparing two dose-fractionations stereotactic body radiotherapy (SBRT) for medically inoperable Stage IA non-small cell lung cancer or small lung lesions clinically diagnosed as primary lung cancer: Japan Clinical Oncology Group Study JCOG1408 (J-SBRT trial) [O] . Tomoki Kimura, Yasushi Nagata, Junko Eba, 2017

机译：用于比较两种剂量分数立体定向体放射治疗（SBRT）的随机期III试验IA非小细胞肺癌或小肺病变临床诊断为原发性肺癌：日本临床肿瘤学群体研究JCOG1408（J-SBRT试验）
8. Phase 1 Trial of an Immune Checkpoint Inhibitor plus Stereotactic Ablative Radiotherapy in Patients with Inoperable Stage I Non-Small Cell Lung Cancer. [R] . Kelly, K., Monjazeb, A., Daly, M., 2017

机译：免疫检查点抑制剂加立体定向消融放疗治疗不能手术的I期非小细胞肺癌的1期试验。

SPACE - A randomized study of SBRT vs conventional fractionated radiotherapy in medically inoperable stage I NSCLC

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