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Imaging in Gestational Trophoblastic Disease

机译:在妊娠期滋养细胞疾病中成像

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摘要

Gestational trophoblastic disease (GTD) is a spectrum of disorders characterized by abnormal trophoblastic proliferation. GTD includes benign conditions such as hydatidiform moles and malignant diseases that are referred as gestational trophoblastic neoplasia (GTN). Ultrasound plays a central role in the diagnosis of patients with hydatidiform mole. Other imaging modalities are useful in molar pregnancy, mainly for evaluating pulmonary complications and atypical presentation of hydatidiform mole. GTN typically arises after 20% of molar pregnancies but can uncommonly occur after nonmolar gestations. After uterine evacuation, serial human chorionic gonadotropin levels are evaluated in patients for early detection of GTN. Once GTN is suspected, Doppler ultrasound is the primary tool to confirm the diagnosis; however, magnetic resonance imaging can also help in selected cases. Metastatic disease workup can involve various modalities, including ultrasound, X-ray, computed tomography, magnetic resonance imaging and positron emission tomography/computed tomography. In this article, we review the main imaging modalities used to evaluate patients with GTD. (C) 2019 Elsevier Inc. All rights reserved.
机译:妊娠期滋养细胞疾病(GTD)是一种疾病,其特征在于滋养细胞异常增殖。 GTD包括良性条件,如囊状痣和恶性疾病,称为妊娠滋养细胞瘤形成(GTN)。超声波在患有瓦尔膜患者的诊断中起着核心作用。其他成像方式可用于摩尔妊娠,主要用于评估肺部并发症和无典型含有瓦尔的非典型呈现。 GTN通常在摩尔妊娠的20%后出现,但在非极性妊娠后可能罕见。在子宫疏散后,在患者早期检测GTN的患者中评估连续人绒毛膜促水平。疑似GTN后,多普勒超声是确认诊断的主要工具;然而,磁共振成像也可以有助于选定的情况。转移性疾病的余处可以涉及各种方式,包括超声波,X射线,计算机断层扫描,磁共振成像和正电子发射断层扫描/计算断层扫描。在本文中,我们审查了用于评估GTD患者的主要成像模态。 (c)2019 Elsevier Inc.保留所有权利。

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