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A preface on advances in diagnostics for infectious and parasitic diseases: detecting parasites of medical and veterinary importance.

机译:传染病和寄生疾病诊断前进的序言:检测医学与兽医寄生虫。

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摘要

There are many reasons why detection of parasites of medical and veterinary importance is vital and where novel diagnostic and surveillance tools are required. From a medical perspective alone, these originate from a desire for better clinical management and rational use of medications. Diagnosis can be at the individual-level, at close to patient settings in testing a clinical suspicion or at the community-level, perhaps in front of a computer screen, in classification of endemic areas and devising appropriate control interventions. Thus diagnostics for parasitic diseases has a broad remit as parasites are not only tied with their definitive hosts but also in some cases with their vectors/intermediate hosts. Application of current diagnostic tools and decision algorithms in sustaining control programmes, or in elimination settings, can be problematic and even ill-fitting. For example in resource-limited settings, are current diagnostic tools sufficiently robust for operational use at scale or are they confounded by on-the-ground realities; are the diagnostic algorithms underlying public health interventions always understood and well-received within communities which are targeted for control? Within this Special Issue (SI) covering a variety of diseases and diagnostic settings some answers are forthcoming. An important theme, however, throughout the SI is to acknowledge that cross-talk and continuous feedback between development and application of diagnostic tests is crucial if they are to be used effectively and appropriately.
机译:为什么检测医疗和兽医寄生虫的原因是至关重要的,并且需要新的诊断和监测工具。从单独的医学角度来看,这些源自渴望更好的临床管理和合理使用药物。诊断可以在个人级别,接近患者设置,在测试临床怀疑或在社区层面,也许在电脑屏幕前,在流行区域的分类和设计适当的控制干预方面。因此,寄生虫疾病的诊断具有广泛的汇率,因为寄生虫不仅与他们的最终宿主联系,而且在某些情况下与他们的载体/中间宿主一起联系起来。当前诊断工具和决策算法在维持控制程序中的应用,或在消除设置中,可能是有问题的,甚至不适用。例如,在资源限制的设置中,目前的诊断工具是否足够强大地用于刻度的操作使用,或者它们是由地面现实的混淆;是公共卫生干预措施的诊断算法始终理解,并在针对控制的社区内得到了良好的?在这个特殊问题中(SI)涵盖各种疾病和诊断设置一些答案即将到来。然而,在整个SI中,一个重要的主题是承认,如果要有效且适当地使用,诊断测试的开发和应用之间的串扰和连续反馈是至关重要的。

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