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首页> 外文期刊>The Journal of Antibiotics: An International Journal >Absolute stereostructures of chaetomugilins G and H produced by a marine-fish-derived Chaetomium species.
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Absolute stereostructures of chaetomugilins G and H produced by a marine-fish-derived Chaetomium species.

机译:由海洋鱼类衍生的Chaetomiencies生产的Chaetomugilins G和H的绝对立体结构。

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摘要

Chaetomugilins G and H were isolated from a strain of Chaetomium globosum that was originally isolated from the marine fish, Mugil cephalus, and their absolute stereostructures were elucidated on the basis of spectroscopic analyses, including 1D and 2D NMR techniques, and chemical transformation. In addition, the absolute configuration of chaetoviridin C was established by derivatization from chaetomugilin A. These compounds exhibited a growth inhibitory activity against cultured P388, HL-60, L1210 and KB cells.
机译:从最初从海洋鱼类,穆格尼尔头部分离出来的Chaetomium血液质量的菌株中分离出噬菌体蛋白G和H,并在光谱分析的基础上阐明它们的绝对立体结构,包括1D和2D NMR技术和化学转化。 此外,通过从Chaetomugilin A的衍生化建立了Chaetoviridin C的绝对构型。这些化合物表现出对培养的P388,HL-60,L1210和KB细胞的生长抑制活性。

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