• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>The Journal of Reproduction and Development >Studying the variations in differently expressed serum proteins of Hainan black goat during the breeding cycle using isobaric tags for relative and absolute quantitation (iTRAQ) technology
【24h】

Studying the variations in differently expressed serum proteins of Hainan black goat during the breeding cycle using isobaric tags for relative and absolute quantitation (iTRAQ) technology

机译：使用异源标签在育种周期中使用异常和绝对定量（ITRAQ）技术研究繁殖周期不同表达海南黑山羊不同表达血清蛋白的变化

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The Hainan black goat is a high-quality local goat breed in Hainan Province of China. It is resistant to high temperatures, humidity, and disease. Although the meat of this breed is tender and delicious, its reproductive performance and milk yield are low. In this study, isobaric tags for relative and absolute quantitation (iTRAQ) technology was used to analyze the differentially expressed proteins in the serum of female Hainan black goats during the reproductive cycle (empty pregnant, estrus, gestation, and lactation). The pathway enrichment analysis results showed that most of the differentially expressed proteins between each period belonged to the complement and coagulation cascades. Analysis of the differential protein expression and function revealed seven proteins that were directly associated with reproduction, namely pre-SAA21, ANTXR2, vWF, SFRP3, beta 4GalT1, pre-IGFBP2 and Ran. This study revealed the changing patterns of differentially expressed proteins in the reproductive cycle of the Hainan black goat. pre-SAA21, ANTXR2, vWF, SFRP3, beta 4GalT1, pre-IGFBP2, and Ran were identified as candidate proteins for mediating the physiological state of Hainan black goats and regulating their fertility. This study elucidated the changes in expression levels of differentially expressed proteins during the reproductive cycle of Hainan black goats and also provides details about its breeding pattern.
机译：海南黑山羊是中国海南省的高品质本地山羊品种。它是耐高温，湿度和疾病的耐受性。虽然这种品种的肉类嫩且美味，但其繁殖性能和牛奶产量很低。在这项研究中，用于相对和绝对定量（ITRAQ）技术的等因素标签用于分析生殖循环期间雌性海南黑山羊血清中的差异表达蛋白质（空孕妇，妊娠，妊娠和哺乳期）。途径富集分析结果表明，每个时期之间的大多数差异表达的蛋白质属于补体和凝固级联。差异蛋白表达和功能的分析显示出与繁殖的七种蛋白质，即SAA21，ANTXR2，VWF，SFRP3，β4gALT1，Pre-IgBP2和RAN直接相关。本研究揭示了海南黑山羊生殖周期中的差异表达蛋白质的变化模式。 SAA21，ANTXR2，VWF，SFRP3，BETA 4GALT1，前IGFBP2和RAN被鉴定为用于调解海南黑山羊的生理状态并调节其生育的候选蛋白。本研究阐明了海南黑山羊生殖周期中差异表达蛋白质表达水平的变化，并提供有关其繁殖模式的细节。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号