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Clinical trials: new opportunities.

机译:临床试验:新的机会。

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摘要

Human cognitive aging has been too long neglected and underappreciated for its critical importance to quality of life in old age. The articles in this session present novel approaches to improving cognitive function in normal aging persons with drugs and interventions that are based on findings in epidemiology, studies in aged animals, and in vitro research. In addition, since aging is the primary risk factor for Alzheimer's disease, these studies also have implications as interventions for prevention and treatment. As a field of research, new knowledge regarding the causes and mechanisms of cognitive aging are ripe for translation into human studies, with the application of this knowledge leading the development of interventions and therapeutics for the prevention of cognitive decline in old age and Alzheimer's disease.
机译:人类认知老龄化已经过于长期忽视并低估了对晚年生活质量至关重要。 本届会议的文章目前提出了改善正常老龄化人的认知功能的新方法,这些方法是基于流行病学的研究结果,年龄的动物研究和体外研究的药物和干预措施。 此外,由于老化是阿尔茨海默病的主要风险因素,这些研究也具有作为预防和治疗的干预措施的影响。 作为研究领域,关于认知老龄化的原因和机制的新知识对于人类研究成熟,在人类研究中,应用了这些知识,从而引发了预防老年和阿尔茨海默病的认知下降的干预措施和治疗方法。

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