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HIV vaccine preparedness studies in the organization for economic co-operation and development (OECD) countries.

机译:经济合作与发展组织(OECD)国家中的HIV疫苗准备研究。

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HIV vaccine development remains an urgent priority. This article is a systematic review of HIV vaccine preparedness studies in the high-income 30 Organization for Economic Co-operation and Development countries, to identify factors important for HIV vaccine trial development in injection drug users (IDU), men who have sex with men (MSM), and women at heterosexual risk (WAHR) across these countries. Of 27 articles we identified, willingness to participate (WTP) was assessed in eight studies involving IDU, 11 involving MSM, and one involving WAHR. WTP ranged in IDU at 41-86%, MSM at 23-94%, and in WAHR, it was at 81%. Studies reported recruitment of high-risk individuals. Retention was assessed in eight studies involving IDU, five involving MSM, and three involving WAHR. IDU were retained at a range of 3-98%, MSM at 70-95% and WAHR at 67-92%. This review provides an in-depth summary of HIV vaccine preparedness studies that were conducted in the Organization for Economic Co-operation and Development countries.
机译:艾滋病毒疫苗的开发仍然是当务之急。本文是对高收入30个经济合作与发展组织国家中HIV疫苗准备研究的系统综述,以确定对注射吸毒者(IDU)(与男人发生性关系的男性)中HIV疫苗试验开发的重要因素(MSM),以及这些国家/地区中处于异性恋风险中的女性(WAHR)。在我们确定的27篇文章中,参与IDU的八项研究,涉及MSM的11项和涉及WAHR的一项研究评估了参与意愿(WTP)。 IDU的WTP范围为41-86%,MSM的范围为23-94%,WAHR的范围为81%。研究报告招募高风险个人。在八项涉及IDU,五项涉及MSM和三项涉及WAHR的研究中评估了保留率。 IDU保留在3-98%的范围内,MSM保留在70-95%的范围内,WAHR保留在67-92%的范围内。这次审查提供了在经济合作与发展组织国家中进行的艾滋病毒疫苗准备研究的深入总结。

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