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首页> 外文期刊>AIDS Research and Human Retroviruses >Molecular epidemiology of human immunodeficiency virus type 1 and hepatitis C virus in former blood donors in central China.
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Molecular epidemiology of human immunodeficiency virus type 1 and hepatitis C virus in former blood donors in central China.

机译:中国中部前献血者中1型人类免疫缺陷病毒和C型肝炎病毒的分子流行病学。

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摘要

The prevalence of hepatitis C virus (HCV) among human immunodeficiency virus (HIV-1)-positive former blood donors (FBDs) in Hubei province, central China, and the subtypes of these two viruses are identified. HIV-1-positive specimens were collected from FBDs, transfusion recipients, and their sexual partners in Hubei province, central China. The prevalence of HCV in HIV-1-positive FBDs was 78.6%. The dominant circulating HIV-1 subtype of FBDs was subtype B' (Thai-B); one belonged to U.S.-European subtype B. HCV genotypes 2a (78.6%) and 1b (21.4%) were detected. No recombinant form of HIV-1 was identified. Non-B' subtypes occurring among FBDs indicate the complexity of the HIV-1 prevalence in central China, where HIV is beginning to spread into the general population.
机译:在中国中部湖北省,在人类免疫缺陷病毒(HIV-1)阳性的原献血者(FBD)中,丙型肝炎病毒(HCV)的流行情况以及这两种病毒的亚型得以确定。 HIV-1阳性标本来自中国中部湖北省的FBD,输血接受者及其性伴侣。 HIV-1阳性FBD中的HCV患病率为78.6%。 FBD的主要循环HIV-1亚型为B'亚型(Thai-B);其中一种属于美欧B型。检测到HCV基因型2a(78.6%)和1b(21.4%)。没有鉴定出HIV-1的重组形式。在FBD中发生的非B'亚型表明,中国中部地区HIV-1流行的复杂性,那里的HIV开始向普通人群传播。

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