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首页> 外文期刊>Heart, lung & circulation >Evaluation of Cognitive Function Following Transcatheter Aortic Valve Replacement
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Evaluation of Cognitive Function Following Transcatheter Aortic Valve Replacement

机译：经导管主动脉瓣膜置换后认知功能评估

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BackgroundTranscatheter aortic valve replacement (TAVR) is associated with procedural-related neurological events and acute cognitive decline. However, data on the effect of TAVR on mid-term cognitive outcome are scarce. Therefore, we aimed to assess the impact of TAVR on mid-term cognitive outcome using different neurocognitive test batteries. MethodsPatients with severe aortic valve stenosis scheduled for TAVR were enrolled. Cognitive assessment was performed at baseline and 4 months post-TAVR using an eight-word verbal-learning test (“Immediate Recall Memory Test” [IRMT], “Delayed Recall Memory Test” [DRMT], “Recognition of Verbal Information Test” [RVIT]), global cognitive function (“Mini Mental State Examination” [MMSE]), and executive function (“Trail Making Test” [TMT], “Clock-Drawing Test” [CDT]). ResultsA total of 30 patients (age: 81±6years, logistic EuroSCORE: 19±10%) completed the follow-up cognitive assessments. Postoperatively, 17% (n=5) developed delirium, 13% (n=4) received permanent pacemaker, and there were no cerebrovascular events. Mean hospital duration time was 5±2 days. Patients (n=22) who did not complete the follow-up cognitive assessments had comparable baseline, procedural and hospital outcome. At follow-up there was a significant improvement in IRMT (27±5 vs. 30±4, p=0.016), with a trend toward improved DRMT (4±2 vs. 5±2, p=0.079). Moreover, patients with lower baseline MMSE and IRMT improved significantly during the follow-up. ConclusionsTranscatheter aortic valve replacement was associated with an improved IRMT during follow-up. Both MMSE and IRMT were significantly improved among those with lower baseline scores.
机译：BackgroundTranscatheter主动脉瓣更换（TAVR）与程序相关的神经学事件和急性认知下降有关。但是，关于TAVR效果对中期认知结果的数据的数据是稀缺的。因此，我们旨在评估TAVR对使用不同神经认知试验电池的中期认知结果的影响。招募了针对TAVR的严重主动脉瓣狭窄的方法分类剂。在基线和Tavr后4个月内进行认知评估使用八字形言语学习测试（“立即召回记忆测试”[IRMT]，“延迟回忆记忆测试”[DRMT]，“识别口头信息测试”[ RVIT]），全球认知功能（“迷你精神状态检查”[MMSE]）和执行功能（“迹线制作测试”[TMT]，“时钟绘图测试”[CDT]）。结果总共30名患者（年龄：81±6年，物流Euroscore：19±10％）完成后续认知评估。术后，17％（n = 5）开发的谵妄，13％（n = 4）接受了永久起搏器，没有脑血管事件。平均医院持续时间为5±2天。患者（n = 22）没有完成后续认知评估的谁具有可比的基线，程序和医院结果。在后续随访时，IRMT的显着改善（27±5比±4，P = 0.016），趋势改善DRMT（4±2对5±2，P = 0.079）。此外，在随访期间，较低的基线MMSE和IRMT的患者显着提高。结案在随访期间，结论术后瓣膜瓣膜置换与改善的IRMT相关。在基线评分较低的人中，MMSE和IRMT都显着改善。

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