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首页> 外文期刊>Journal of biomedical materials research. Part B, Applied biomaterials. >Influence of cement stiffness and bone morphology on the compressive properties of bone-cement composites in simulated vertebroplasty.
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Influence of cement stiffness and bone morphology on the compressive properties of bone-cement composites in simulated vertebroplasty.

机译：水泥刚度与骨形态对模拟椎体成形术中骨水泥复合材料压缩性能的影响。

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Vertebroplasty is widely used to treat vertebral compression fractures. Little is known about the influence of morphological parameters of the bone on the properties of the bone-cement composite. Furthermore, although generic finite element (FE) models have been suggested as a way to compute the values of these properties, their accuracy has not been established. In the experimental part of this study, we tested bovine cancellous bone and three different polymethylmethacrylate bone cements and determined six quasi-static uniaxial compressive properties of bone-cement composite specimens and 10 morphological parameters of the bone. For the FE work, we used two simulations, one being μFE and the other unit cell FE. In conclusion, we found that (1) for composite specimens, that relative contribution of the cement to the overall response of the composite increases with increasing cement stiffness; (2) the anisotropy ratio is the bone morphological property that exerts the most significant influence on the experimentally obtained compressive properties of the bone-cement composites determined; (3) the accuracy of the computed compressive properties of the composites ranged from low to high, depending on simulation method used. The largest errors, however, can partially be explained by difference in boundary conditions between the experimental testing and the simulation techniques. The lattermost finding points to the potential for simplified FE models being incorporated into automatic material mapping schemes in whole bone vertebra FE simulations.
机译：椎体成形术广泛用于治疗椎体压缩骨折。关于骨形态参数对骨水泥复合物性能的影响很少。此外，尽管已经建议了通用有限元（FE）模型作为计算这些属性值的方法，但它们的准确性尚未建立。在本研究的实验部分中，我们测试了牛松散骨和三种不同的聚甲基丙烯酸甲酯骨水泥，并确定了骨水泥复合标本的六种准静态单轴压缩性能和骨的10个形态参数。对于FE工作，我们使用了两种模拟，一个是μFE和其他单元电池FE。总之，我们发现（1）用于复合标本，水泥对复合材料的整体反应的相对贡献随着水泥刚度的增加而增加; （2）各向异性率是对确定的骨水泥复合材料的实验获得的压缩性质产生最显着影响的骨形态特性; （3）复合材料的计算压缩性能的精度范围从低到高，这取决于所使用的仿真方法。然而，可以通过实验测试和模拟技术之间的边界条件的差异来分析最大的误差。最重要的发现指向简化的FE模型的潜力被纳入全骨椎骨模拟中的自动材料映射方案。

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