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首页> 外文期刊>Journal of cardiology >Different effects of exercise training in patients with myocardial infarction with or without diabetes mellitus
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Different effects of exercise training in patients with myocardial infarction with or without diabetes mellitus

机译：在心肌梗死患者中锻炼训练的不同效果或没有糖尿病

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OBJECTIVES: This study investigated whether myocardial infarction patients with diabetes mellitus had lower heart rate reserve to exercise by measuring the increment in heart rate (HR) divided by the increment of norepinephrine (NE) concentration from rest to peak exercise (delta HR/log delta NE). The difference in exercise training effects was also investigated. METHODS: The 148 patients after myocardial infarction were divided into two groups, the DM group (n = 34) and the non-DM group (n = 114). Cardiopulmonary exercise testing was performed in each subject at 1 and 3 months after the onset. Blood samples were taken at rest and immediately after peak exercise, rest brain natriuretic peptide, rest and peak norepinephrine were analyzed. Exercise training was performed from 1 to 3 months after the onset. RESULTS: Resting heart rates were significantly higher in the DM group than in the non-DM group both at 1 and 3 months although peak heart rates were not significantly different. Peak oxygen uptake were lower in the DM group both at 1 and 3 months after onset of myocardial infarction compared to the non-DM group. End-tidal carbon dioxide pressure was lower and the rate of increase of minute ventilation to carbon dioxide output was higher in the DM group. Plasma brain natriuretic peptide was higher in the DM group. delta HR/log delta NE was 19.4 +/- 4.0 in the DM group and 22.2 +/- 5.6 in the non-DM group (p < 0.01), and increased in only the non-DM group. delta HR/log delta NE was more closely correlated with peak oxygen uptake in the DM group than in the non-DM group. CONCLUSIONS: Impaired response to exercise training may be caused, in part, by impaired heart rate reserve to exercise in patients with diabetes mellitus.
机译：目的：本研究调查了糖尿病患者的心肌梗死患者是否通过测量心率（HR）的增量除以从静止至峰锻炼（Delta Hr / Log Delta）的心率（HR）的增量除以心率（HR）的增量来进行较低的心率储备。 ne）。还调查了运动培训效应的差异。方法：将148名患者分为两组，DM组（n = 34）和非DM组（n = 114）。在发病后1和3个月的每个受试者中进行了心肺运动测试。血液样品在休息时拍摄，并在峰锻炼后立即进行分析，休息脑钠肽，静息和峰比肾上腺素。发病后1至3个月的运动培训。结果：DM组休息心率明显高于1和3个月，虽然峰值心率没有显着不同。与非DM组相比，在心肌梗塞发生后1和3个月，DM组在DM组中较低。潮端二氧化碳压力较低，在DM组中，对二氧化碳输出的微小通风速率较高。 DM组血浆脑钠尿肽较高。 Delta HR / Log Delta NE是DM组的19.4 +/- 4.0，非DM组中的22.2 +/- 5.6（P <0.01），仅在非DM组中增加。 Delta HR / Log Delta Ne与DM组中的峰值吸收更密切相关，而不是非DM组。结论：可能造成对运动培训的损害，部分是由糖尿病患者的心率储备受损的心率储备造成的。

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