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Is Kaposi's sarcoma occurring at higher CD4 cell counts over the course of the HIV epidemic?

机译:在艾滋病流行期间,卡波西氏肉瘤是否以较高的CD4细胞计数发生?

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摘要

We evaluated longitudinal rates of Kaposi's sarcoma and trends in CD4 cell counts at the time of Kaposi's sarcoma diagnosis during the HIV epidemic (1985-2008). Although rates of Kaposi's sarcoma have decreased, cases are now occurring at higher CD4 cell counts over time, with more than one-third of cases diagnosed in 2002-2008 occurring at CD4 cell counts of at least 350 cells/mul. These data support future studies evaluating the impact of highly active antiretroviral therapy initiation at higher CD4 cell counts to further reduce Kaposi's sarcoma.
机译:我们评估了艾滋病流行期间(1985-2008年)卡波西肉瘤诊断时卡波西肉瘤的纵向发病率和CD4细胞计数趋势。尽管卡波西氏肉瘤的发病率有所下降,但随着时间的推移,现在的病例中CD4细胞计数更高,2002-2008年诊断出的病例中,有三分之一以上的CD4细胞计数至少为350细胞/ mul。这些数据支持未来的研究,以评估高活性抗逆转录病毒疗法对更高CD4细胞计数的影响,以进一步减少卡波济氏肉瘤。

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