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首页> 外文期刊>Journal of dentistry >The caries continuum: Opportunities to detect, treat and monitor the re-mineralization of early caries lesions
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The caries continuum: Opportunities to detect, treat and monitor the re-mineralization of early caries lesions

机译：龋齿连续统一体：检测，治疗和监测早期龋病的重新矿化的机会

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摘要

The aim of this review is to discuss dental caries as a dynamic process of de-mineralization and re-mineralization with progression, arrest or reversal of lesions reflecting the balance between them. The need for new clinical trial designs to assess oral care products which reflect and monitor these processes is highlighted and discussed. The research evidence to support the use of two state-of-the-art methods that focus on re-mineralization of natural root caries lesions and natural enamel lesions is described. The use of the Electrical Caries Monitor (ECM) in combination with clinical scoring of lesions to assess the hardness of root dentin and the use of Quantitative Light-induced Fluorescence (QLF) to measure enamel lesions are described together with a number of studies that have employed the methods to assess the efficacy of oral care products. It can be concluded that quantification of the re-mineralization provided by oral care products assessed using both buccal caries and root caries study designs is a valid approach to developing understanding of the mechanism of action of a new technology and to establishing its clinical efficacy in respect of arresting and reversing early caries lesions, and it complements, enhances and may ultimately supplant the information from a conventional two- to three-year clinical trial measuring effects at the cavitation level.
机译：本综述的目的是讨论龋齿，作为脱矿和重新矿化的动态过程，并在进展，逮捕或逆转的病变反映它们之间的平衡。需要新的临床试验设计，以评估反映和监测这些过程的口腔护理产品被突出显示并讨论。描述了支持使用专注于重新矿化和天然牙釉质病变的重新矿化的最新方法的研究证据。使用电气龋齿监测器（ECM）与病变的临床评估结合以评估根牙本质的硬度和使用定量光诱导的荧光（QLF）来测量牙釉质病变的研究与许多研究一起描述采用这些方法来评估口腔护理产品的功效。可以得出结论，使用颊龋和根龋病研究设计评估的口腔护理产品提供的重新矿化的定量是制定对新技术的行动机制以及在尊重方面建立临床疗效的有效方法逮捕和逆转早期龋病病变，它补充，增强，并可能最终取代了在空化水平的传统两年至三年临床试验测量效果中的信息。

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