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首页> 外文期刊>Journal of dentistry >In situ effect of a commercial CPP-ACP chewing gum on the human enamel initial erosion
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In situ effect of a commercial CPP-ACP chewing gum on the human enamel initial erosion

机译：原位效应商业CPP-ACP口香糖对人类珐琅质初始侵蚀的影响

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Methods Seventy-two human enamel blocks, after selection (initial surface hardness - SHi) and in vitro short-term acidic exposure (cola drink for 3 min - SHd) were randomly assigned to three groups. The factors under study were treatment (3 levels: GI chewing gum with CPP-ACP, GII chewing gum without CPP-ACP and GIII control group without gum) and intraoral period (2 levels: 2 and 24 h). Twelve volunteers wore intraoral palatal devices for 24 h in 3 crossover phases. On each phase, after 2 h the surface hardness was assessed (SHf1) and the blocks were reinserted and the devices were used for additional 22 h (SHf2). In phases of GI and GII volunteers chewed the respective gum during 30 min, for 4 times with an interval of 4 h. Percentage of surface hardness recovery (%SHR) was calculated after 2 and 24 h. The data were analysed by repeated measures ANOVA and Tukey's test.Results Chewing gum with CPP-ACP (2 h = 50.0% < 24 h = 95.9%) showed higher hardness recovery than chewing gum without CPP-ACP (2 h = 30.0% < 24 h = 71.1%) and control (2 h = 15.7% < 24 h = 40.9%) (p < 0.05).Conclusions The results suggest that saliva increased hardness of softened enamel after the use of conventional chewing gum (GII) and this effect was enhanced by the prolonged intraoral period (24 h) and by the use of CPP-ACP chewing gum (GI).Clinical significance Since chewing gum is an alternative to enhance salivary defenses after erosive challenges, CPP-ACP chewing gum might be a supplementary strategy to potentiate the mineral precipitation of initial erosion lesions.Objective This study evaluated the in situ rehardening effect of a commercial chewing gum containing casein phosphopeptide - amorphous calcium phosphate (CPP-ACP) on initial erosion lesions.
机译：方法将七十二人牙釉质块，选择（初始表面硬度 - Shi）和体外短期酸性暴露（3 min-Shd）的体外短期酸性暴露（3 min-shd）进行了三组。研究的因素是治疗（3级：GI口香糖，CPP-ACP，GII口香糖，没有CPP-ACP和GIII对照组，没有胶）和内部期间（2级：2和24小时）。 12个志愿者在3个交叉阶段穿过24小时的内部腭装置。在每相上，在2小时后，评估表面硬度（SHF1），再插入嵌段，并将装置用于另外22小时（SHF2）。在GI和GII志愿者的阶段，在30分钟内咀嚼相应的口香糖，4次，间隔为4小时。表面硬度恢复的百分比（％SHR）在2至24小时后计算。通过重复测量Anova和Tukey的测试分析数据。药物与CPP-ACP的口香糖（2小时= 50.0％<24h = 95.9％）显示出比没有CPP-ACP的口香糖更高的硬度恢复（2小时= 30.0％< 24h = 71.1％）和对照（2小时= 15.7％<24h = 40.9％）（P <0.05）。结论结果表明，在使用常规口香糖（GII）之后，唾液将增加软化珐琅的硬度增加通过延长的内部（24小时）和使用CPP-ACP口香糖（GI）的效果增强。由于口香糖术后，使用CPP-ACP口香糖口香糖（GI）是临床意义，是在侵蚀挑战后提高唾液防御的替代方案，CPP-ACP口香糖可能是一个补充策略提高初始侵蚀病变的矿物沉淀。目的本研究评估了含有酪蛋白磷酸肽 - 无定形磷酸盐（CPP-ACP）的商业口香糖的原位重度效果在初始侵蚀病变上。

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