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The ongoing evolution of laser desorption/ionization mass spectrometry: Some observations on current trends and future directions

机译：激光解吸/电离质谱的持续发展：关于当前趋势和未来方向的一些观察

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Abstract >The practice of laser desorption/ionization (LDI) mass spectrometry continues to evolve. In the most commonly adopted manifestation of LDI, matrix assisted LDI, attention continues to be directed towards novel sample application strategies and modifications to the sample plate. Specifically, researchers continue to explore adaptations to the conventional, stainless steel sample plate that is the centerpiece of conventional LDI. Numerous variants of LDI‐MS have been reported based on modifications of the plate surface, but none of these is widely adopted, either by end‐users or by instrument manufacturers. Further, at this time, advances in surface engineering have had only modest impact on day‐to‐day operation. In this article, we review and discuss some of the numerous, but scattered reports on novel LDI strategies with an emphasis on modified sample support substrates and plates. We discuss and highlight innovations that have the potential to markedly enhance the utility of LDI‐MS. </abstract> </span> <span class="z_kbtn z_kbtnclass hoverxs" style="display: none;">展开▼</span> </div> <div class="translation abstracttxt"> <span class="zhankaihshouqi fivelineshidden" id="abstract"> <span>机译：</span><abstract xmlns =“http://www.wiley.com/namespaces/wiley”type =“main”xml：lang =“en”> <title type =“main”>抽象</ title> >练习激光解吸/电离（LDI）质谱持续发展。在最常见的LDI表现形式下，矩阵辅助LDI，注意力继续指向新颖的示例应用策略和对样品板的修改。具体而言，研究人员继续探索对常规LDI的核心的传统不锈钢样品板的适配。已经根据板表面的修改报告了LDI-MS的许多变型，但是这些都不是通过最终用户或仪器制造商广泛采用这些变体。此外，此时，表面工程的进步已经对日常运营产生了适度的影响。在本文中，我们审查并讨论了一些关于新型LDI策略的一些但分散的报告，重点是改进的样品支持基板和板块。我们讨论并突出有可能显着增强LDI-MS的效用的创新。</ p> </ abstract> </span> <span class="z_kbtn z_kbtnclass hoverxs" style="display: none;">展开▼</span> </div> </div> <div class="record"> <h2 class="all_title" id="enpatent33" >著录项</h2> <ul> <li> <span class="lefttit">来源</span> <div style="width: 86%;vertical-align: text-top;display: inline-block;"> <a href='/journal-foreign-34906/'>《Journal of mass spectrometry: JMS》</a> <b style="margin: 0 2px;">|</b><span>2018年第6期</span><b style="margin: 0 2px;">|</b><span>共16页</span> </div> </li> <li> <div class="author"> <span class="lefttit">作者</span> <p id="fAuthorthree" class="threelineshidden zhankaihshouqi"> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Muthu Manikandan&option=202" target="_blank" rel="nofollow">Muthu Manikandan;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Chun Sechul&option=202" target="_blank" rel="nofollow">Chun Sechul;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Wu Hui‐Fen&option=202" target="_blank" rel="nofollow">Wu Hui‐Fen;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Duncan Mark W.&option=202" target="_blank" rel="nofollow">Duncan Mark W.;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Gopal Judy&option=202" target="_blank" rel="nofollow">Gopal Judy;</a> </p> <span class="z_kbtnclass z_kbtnclassall hoverxs" id="zkzz" style="display: none;">展开▼</span> </div> </li> <li> <div style="display: flex;"> <span class="lefttit">作者单位</span> <div style="position: relative;margin-left: 3px;max-width: 639px;"> <div class="threelineshidden zhankaihshouqi" id="fOrgthree"> <p>Department of Bioresource and Food ScienceKorea Konkuk UniversitySeoul 143‐701 Korea;</p> <p>Department of Bioresource and Food ScienceKorea Konkuk UniversitySeoul 143‐701 Korea;</p> <p>Department of Chemistry and Center for Nanoscience and NanotechnologyNational Sun Yat‐Sen University70 Lien‐Hai Road Kaohsiung 80424 Taiwan;</p> <p>Division of Endocrinology Metabolism and DiabetesUniversity of Colorado DenverMail Stop 8106 12801 East 17th Avenue Aurora CO 80045 USA;</p> <p>Department of Bioresource and Food ScienceKorea Konkuk UniversitySeoul 143‐701 Korea;</p> </div> <span class="z_kbtnclass z_kbtnclassall hoverxs" id="zhdw" style="display: none;">展开▼</span> </div> </div> </li> <li > <span class="lefttit">收录信息</span> <span style="width: 86%;vertical-align: text-top;display: inline-block;"></span> </li> <li> <span class="lefttit">原文格式</span> <span>PDF</span> </li> <li> <span class="lefttit">正文语种</span> <span>eng</span> </li> <li> <span class="lefttit">中图分类</span> <span><a href="https://www.zhangqiaokeyan.com/clc/1187.html" title="分析化学">分析化学;</a></span> </li> <li class="antistop"> <span class="lefttit">关键词</span> <p style="width: 86%;vertical-align: text-top;"> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=LDI‐MS&option=203" rel="nofollow">LDI‐MS;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=MALDI‐MS&option=203" rel="nofollow">MALDI‐MS;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=miniaturization&option=203" rel="nofollow">miniaturization;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=review&option=203" rel="nofollow">review;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=surface engineering&option=203" rel="nofollow">surface engineering;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=target plates&option=203" rel="nofollow">target plates;</a> </p> <div class="translation"> 机译：LDI-MS;MALDI-MS;小型化;审查;表面工程;目标盘子; 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