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首页> 外文期刊>Journal of orthopaedic research >Semitendinosus muscle fatty infiltration following tendon harvest in rabbits
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Semitendinosus muscle fatty infiltration following tendon harvest in rabbits

机译：在兔子肌腱收获后，肌肉脂肪渗透

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摘要

The hamstring tendon autograft is one of the most commonly used graft choices in Anterior cruciate ligament (ACL) reconstruction. There are conflicting results regarding postoperative hamstring strength deficits in patients who have had a hamstring graft. The semitendinosus tendon has been shown to regenerate after harvesting for ACL autograft, suggesting that the muscle has the potential to regain normal function. However, no studies have been performed to define the microstructural changes that occur in the semitendinosus muscle after tendon resection. In this study, we hypothesized that fatty infiltration of the semitendinosus muscle after tendon harvest in New Zealand White rabbits increases postoperatively and remains constant or increases during the first year of repair. The semitendinosus tendon was unilaterally detached and harvested from 15 rabbits. Five rabbits were sacrificed at 3-, 6-, and 12-month intervals, and the semitendinosus muscle-tendon units were analyzed. The contralateral unoperated limb served as the control. The gross tendon and muscle dimensions and histologic percentage of fatty infiltration were measured. We found no significant difference in fatty infiltration at any time point between the control muscle and test specimens and that there was no progression of fatty infiltration over time. If these results hold true in humans, natural repair of the hamstring muscle following tendon harvest during ACL autograft reconstruction is not inhibited by fatty infiltration.
机译：腿筋肌腱自体移植是前十字韧带（ACL）重建中最常用的移植物选择之一。在患有腿筋移植物的患者中，存在关于术后腿筋强度缺陷的矛盾的结果。在收获ACL自体移植后，已经显示了肌约肌肌腱，表明肌肉有可能重新获得正常功能。然而，没有进行研究以确定肌腱切除后肌腱肌肉中发生的微观结构变化。在这项研究中，我们假设新西兰白兔肌腱收获后，肌腱收获后肥胖渗透术后增加，修复后的第一年仍然是恒定的或增加。肌腱单侧脱离并从15只兔子收获。在3-，6-和12个月的间隔处处于处置五只兔子，分析了肌肉肌腱单元。对侧未经插入的肢体用作控制。测量脂肪渗透的总肌腱和肌肉尺寸和组织学百分比。我们发现在对照肌肉和试样之间的任何时间点都没有显着渗透渗透，并且随着时间的推移没有脂肪渗透的进展。如果这些结果在人类中持有真实，在ACL自体移植重建期间肌腱收获后的腿筋肌肉的自然修复不受脂肪浸润的抑制。

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