...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >Impact of Atrial Natriuretic Peptide Value for Predicting Paroxysmal Atrial Fibrillation in Ischemic Stroke Patients
【24h】

Impact of Atrial Natriuretic Peptide Value for Predicting Paroxysmal Atrial Fibrillation in Ischemic Stroke Patients

机译：心房利尿性肽价值对缺血性脑卒中患者阵发性心房颤动的影响

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Introduction: The impact of atrial natriuretic peptide (ANP) value for predicting paroxysmal atrial fibrillation (pAF) in ischemic stroke patients remains uncertain. Methods: The consecutive 222 ischemic stroke patients (median 77 [IQR 68-83] years old, 93 females) within 48 hours after onset were retrospectively studied. Plasma ANP and brain natriuretic peptide (BNP) levels were simultaneously measured at admission. Of all, 158 patients had no evidence of atrial fibrillation (AF) (sinus rhythm [SR] group), 25 patients had pAF (pAF group), and the other 39 patients had chronic AF (cAF group). We investigated predicting factors for pAF, with focus on ANP, BNP, and ANP/BNP ratio. Results: ANP value was significantly higher in the pAF than in the SR group (97 [50-157] mg/dL versus 42 [26-72] mg/dL, P < .05) and further increased in the cAF group (228 [120-392], P < .05 versus pAF and SR groups). Similarly, the BNP value was higher in the pAF than in the SR group (116 [70-238] mg/dL versus 34 [14-72] mg/dL, P <.05) and further increased in the cAF group (269 [199-423], P < .05 versus pAF and SR groups). ANP/ BNP ratio was lower in the pAF and cAF groups than in the SR group (. 6 [. 51.2] and.7 [.5-1.0] versus 1.3 [. 8-2.4], both P < .05]. Multivariate analysis in the SR and pAF groups (n = 183) demonstrated that age, congestive heart failure, ANP, and BNP, but not ANP/BNP ratio, were independent predictors for detecting pAF. Receiver operating characteristic curve analysis further showed that area under the curve was similar between ANP and BNP (. 76 and .80). Conclusions: ANP may be clinically useful for detecting pAF in ischemic stroke patients as well as BNP. (C) 2017 National Stroke Association. Published by Elsevier Inc. All rights reserved.
机译：介绍：在缺血性脑卒中患者中预测阵发性心房颤动（PAF）的心房Natrietic肽（ANP）值的影响仍然不确定。方法：首次回顾性研究了连续222次缺血性脑卒中患者（中位数77 [IQR 68-83]岁，93例）在48小时内进行了回顾性研究。在入院时同时测量血浆ANP和脑利钠肽（BNP）水平。在所有情况下，158名患者没有心房颤动的证据（AF）（窦性心律[SR]组），25名患者有PAF（PAF组），另外39名患者患有慢性AF（CAF组）。我们调查了PAF预测因素，重点关注ANP，BNP和ANP / BNP比率。结果：PAF的ANP值显着高于SR组（97 [50-157] Mg / DL，与42 [26-72] Mg / DL，P <.05），在CAF组中进一步增加（228 [120-392]，p <.05与PAF和SR组）。类似地，PAF的BNP值高于SR组（116 [70-238] Mg / DL与34 [14-72] Mg / D1，P <.05），在CAF组中进一步增加（269 [199-423]，p <.05与PAF和SR组）。 PAF和CAF组中的ANP / BNP比率低于SR组（。6 [。51.2]和1.7 [.5-1.0]与1.3 [。8-2.4]，P <.05]。多变量SR和PAF组（n = 183）的分析表明，年龄，充血性心力衰竭，ANP和BNP，但不是ANP / BNP比率是用于检测PAF的独立预测因子。接收器操作特征曲线分析进一步显示了该区域曲线在ANP和BNP之间相似（76和.80）。结论：ANP可能对缺血性卒中患者以及BNP检测PAF。（c）2017年国家中风协会。由elsevier Inc.出版的所有权利。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号