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Oral sucrose for pain control in nonneonate infants during minor painful procedures

机译:在次要痛苦手术期间非天性婴儿疼痛控制的口腔蔗糖

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摘要

Purpose: To provide information regarding the effective use of oral sucrose as an analgesic for immunization and venipuncture procedures in the older infant. Data sources: Evidence-based literature including original clinical trials, reviews, and clinical practice guidelines. Conclusions: Most infants are exposed to multiple minor painful procedures during the first year of life. Oral sucrose solution in a 24% concentration at a dose of 2 mL approximately 2 min prior to the painful procedure has been shown effective in reducing pain during immunizations and venipuncture in the outpatient setting in infants aged 1-12 months old. Implications for practice: Oral sucrose solution should be used as a pain reduction intervention in infants up to 12 months of age undergoing minor painful procedures. Its proven effectiveness as an analgesic, low rate of minor adverse events, ease of administration, and excellent availability make sucrose a good choice for this purpose. Additional research is needed regarding dose response in different infant age groups, optimal concentration of sucrose solution, need for multiple sucrose dosing, adjustment for multiple painful procedures, and addition of optimal nonpharmacologic interventions as a combination approach.
机译:目的:提供有关较老婴儿在较老婴儿的免疫和静脉穿刺程序的镇痛药中有效使用口腔蔗糖的信息。数据来源:基于证据的文献,包括原始临床试验,评论和临床实践指南。结论:在生命的第一年,大多数婴儿暴露于多个次要的痛苦手术。在疼痛手术前约2mL的剂量为24%浓度的口腔蔗糖溶液已被证明在减少在1-12个月龄婴儿的婴儿的门诊环境中减少疼痛和静脉曲张。对实践的影响:口服蔗糖溶液应用作婴儿的疼痛减少干预,最多12个月的年龄较小的痛苦程序。其经过验证的有效性作为镇痛,低次要不良事件,易于管理,以及出色的可用性使蔗糖是此目的的好选择。需要额外的研究关于不同婴儿年龄组的剂量反应,蔗糖溶液的最佳浓度,需要多种蔗糖剂量,对多种疼痛程序进行调整,并添加最佳的非物质干预措施作为组合方法。

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