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Elastographic and morphological testicular changes in hypothyroidism - an experimental study

机译：甲状腺功能减退症的弹性图和形态学睾丸变化 - 实验研究

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Introduction: Methimazole-induced hypothyroidism is a clinical problem in the treatment of hyperthyroidism in people and animals and is an example of metabolic disease that can lead to fertility disorders and can give elastographic testicular changes. Material and Methods: Ultrasound elastography using the Esaote MyLab Twice ultrasound system and a morphological examination of testes were performed in seven methimazole-administered (group E) and seven healthy rats (group C). Results: The elasticity ratio of strains in the scrotal wall of the near-field test area to testicular tissue (ELX-T-RAT) and hardness percentage of strained tissues in the defined area of a testicle (ELX-T%HRD) in group E were statistically significantly lower than in group C. The degree of spermatogenesis was statistically significantly higher in group E than in group C and similarly seminiferous tubule diameters in group E were statistically significantly higher than in group C. Body weight and testicular weight in group E were statistically significantly lower than in group C. Conclusion: Changes in the elastographical parameters of testes may result from disorders secondary to hypothyroidism. The usefulness of elastography is noteworthy in the case of evaluation of testis function in patients with some metabolic disorders.
机译：介绍：甲咪唑诱导的甲状腺功能减退症是人和动物治疗甲状腺功能亢进症的临床问题，是可以导致生育障碍的代谢疾病的一个例子，并可以给予弹性睾丸睾丸变化。材料和方法：使用欧斯卡特MyLab的超声弹性术两次超声系统和睾丸的形态学检查在7甲胺施用（e）和七种健康大鼠（C组）中进行。结果：近场测试区域的阴囊壁中菌株的弹性比在睾丸（ELX-T％HRD）中的睾丸组织（ELX-T大鼠）和应变组织的硬度百分比e统计学显着低于C组。e组统计学的精子发生程度明显高于C组，e组中的类似血管小管直径统计学显着高于C组中C组体重和睾丸重量。在统计学上显着低于C组。结论：睾丸的弹性参数的变化可能由次甲基酮中的紊乱产生。在一些代谢障碍患者的睾丸功能评估的情况下，弹性成像的有用性是值得注意的。

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