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Coronaviruses in avian species - review with focus on epidemiology and diagnosis in wild birds

机译:禽类种类的冠状病毒 - 重点关注野生鸟类流行病学和诊断

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Coronaviruses (CoVs) are a large group of enveloped viruses with a single-strand RNA genome, which continuously circulate in mammals and birds and pose a threat to livestock, companion animals, and humans. CoVs harboured by avian species are classified to the genera gamma- and deltacoronaviruses. Within the gamma-CoVs the main representative is avian coronavirus, a taxonomic name which includes the highly contagious infectious bronchitis viruses (IBVs) in chickens and similar viruses infecting other domestic birds such as turkeys, guinea fowls, or quails. Additionally, IBVs have been detected in healthy wild birds, demonstrating that they may act as the vector between domestic and free-living birds. Moreover, CoVs other than IBVs, are identified in wild birds, which suggests that wild birds play a key role in the epidemiology of other gammaCoVs and deltaCoVs. Development of molecular techniques has significantly improved knowledge of the prevalence of CoVs in avian species. The methods adopted in monitoring studies of CoVs in different avian species are mainly based on detection of conservative regions within the viral replicase, nucleocapsid genes, and 3'UTR or 5'UTR. The purpose of this review is to summarise recent discoveries in the areas of epidemiology and diagnosis of CoVs in avian species and to understand the role of wild birds in the virus distribution.
机译:冠状病毒(COVS)是一大群囊肿病毒,具有单链RNA基因组,其在哺乳动物和鸟类中连续循环,对畜牧,伴侣动物和人类构成威胁。由禽类物种瘫痪的COV被分类为GAMMA-和DELTACORONAVIRUSES。在伽玛-COV中,主要代表是禽冠状病病毒,一种分类名称,包括鸡的高度传染性的传染性支气管炎病毒(IBV)和感染其他家庭鸟类等其他家庭鸟类,如火鸡,几内亚家禽或鹌鹑。此外,IBV已经在健康的野生鸟类中检测到,证明他们可以充当国内和自由生鸟类之间的载体。此外,除IBV之外的COVS在野生鸟类中被鉴定,这表明野生鸟类在其他伽马河和Deltacovs的流行病学中发挥着关键作用。分子技术的发展在禽类种类中显着提高了COVS患病率的知识。在不同禽类种类中监测研究中采用的方法主要基于检测病毒复制酶,核衣壳基因和3'UTR或5'UTR的保守区域。本综述的目的是总结最近在禽类种类的流行病学和诊断中的发现,并了解野生鸟类在病毒分布中的作用。

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