We agree with the sentiments expressed by Lodge et al. that the data in relation to avoiding cow's milk and substituting this with extensively or partially hydrolysed whey or casein formulas in high risk infants who are unable to breast-feed need to be interpreted with caution. It is for this reason that we emphasized the modest quantity and quality of the evidence, and the need for further research (1). Whilst we recognize the problems with drawing definitive conclusions from the current evidence base, given that food allergy now affects so many children (2), it is also important to take a practical approach to interpreting these data such that the evidence has the potential to help clinicians.
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