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首页> 外文期刊>Allergy >IgE recognition patterns in peanut allergy are age dependent: perspectives of the EuroPrevall study
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IgE recognition patterns in peanut allergy are age dependent: perspectives of the EuroPrevall study

机译：花生过敏中的IgE识别模式取决于年龄：EuroPrevall研究的观点

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Seventy-eight percent of peanut allergics were sensitized to peanut extract and 90% to at least one peanut component. rAra h 2 was the sole major allergen for the peanut-allergic population. Geographical differences were observed for rAra h 8 and rAra h 9, which were major allergens for central/western and southern Europeans, respectively. Sensitization to rAra h 1 and 2 was exclusively observed in early-onset peanut allergy. Peanut-tolerant subjects were frequently sensitized to rAra h 8 or 9 but not to storage proteins. Sensitization to Ara h 2 e 1.0 kUA/l conferred a 97% probability for a systemic reaction (P = 0.0002). Logistic regression revealed a significant influence of peanut extract sensitization and region on the occurrence of systemic reactions (P = 0.0185 and P = 0.0436, respectively).
机译：百分之七十八的花生过敏剂对花生提取物敏感，百分之九十对至少一种花生成分敏感。 rAra h 2是花生过敏人群的唯一主要过敏原。观察到rAra h 8和rAra h 9的地理差异，它们分别是中欧/西欧和南欧人的主要过敏原。仅在早发性花生过敏中观察到对rAra h 1和2的致敏作用。耐花生的对象经常对rAra h 8或9敏感，但对储存蛋白不敏感。敏化至Ara h 2 e 1.0 kUA / l赋予了全身反应的97％概率（P = 0.0002）。 Logistic回归显示花生提取物的致敏性和区域对全身性反应的发生有显着影响（分别为P = 0.0185和P = 0.0436）。

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