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首页> 外文期刊>感染症学雑誌 >Measles antibody followed after measles vaccination: comparison with gelatin beads agglutination (PA) antibody, hemagglutination inhibition (HI) antibody and IgG-avidity
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Measles antibody followed after measles vaccination: comparison with gelatin beads agglutination (PA) antibody, hemagglutination inhibition (HI) antibody and IgG-avidity

机译：麻疹抗体后疫苗接种后：与明胶珠凝集（PA）抗体，血凝抑制（HI）抗体和IgG-Avity的比较

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摘要

The immunity status of 37 cases has been tested at 6 weeks and 3.5 years after vaccination by using gelatin beads agglutination (PA), hemagglutination inhibition (HI) and avidity of specific IgG. The geometric mean titer (GMT) of HI antibody was 34.5 at 6 weeks and had fallen to 17.9 over 3.5 years. On the other hand, GMT of PA antibody was 36.5 at 6 weeks and had increased to 286.0 over 3.5 years. Also, the average of measles specific IgG avidity was 4.5% at 6 week and had increased to 45.4% over 3.5 years. The multiple regression analysis was performed in order to investigate the relationship of HI antibody and avidity to PA antibody. The significant involvement of the HI antibody and avidity to PA antibody (standardized partial regression coefficients; 0.612, 0.726) was recognized and the multiple correlation coefficient was 0.880 (p < 0.001). Hence it was strongly suggested that the increase of PA antibody with time could be dependent on that of IgG avidity.
机译：通过使用明胶珠凝集（PA），血晶抑制（HI）和特定IgG的嗜热性，在6周和3.5岁处进行了37例和3.5岁的抗扰度状态。 高抗体的几何平均滴度（GMT）在6周内为34.5次，并在3.5岁以下跌至17.9。 另一方面，在6周的Pa抗体的GMT为36.5，超过386.0超过3.5岁。 此外，6周的6周的麻疹特异性IgG亲和力的平均值为4.5％，超过35.4％。 进行多元回归分析，以研究Hi抗体和亲和力对Pa抗体的关系。 HI抗体和亲和力对PA抗体的显着累及（标准化的部分回归系数; 0.612,0.726），并且多个相关系数为0.880（p <0.001）。 因此强烈建议，随着时间的推移，PA抗体的增加可能依赖于IgG亲密的抗体。

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