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首页> 外文期刊>感染症学雑誌 >Primary pulmonary cryptococcosis exhibiting the radiological characteristics of bronchiolitis obliterans organizing pneumonia
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Primary pulmonary cryptococcosis exhibiting the radiological characteristics of bronchiolitis obliterans organizing pneumonia

机译：初级肺部密度显以表现出支气管炎的放射性特征梗死组织肺炎

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A 31-year-old male was admitted to Toranomon Hospital because of a cough and bilateral patchy infiltrates shown on the chest radiograph. He had been well prior to admission. Chest CT scan revealed patchy areas of air-space consolidation with air-bronchogram and adjacent ground-glass opacities, suggestive of bronchiolitis obliterans organizing pneumonia (BOOP). Transbronchial lung biopsy specimen confirmed the formation of epithelioid cell granulomas without necrosis and the coexistence of organizing pneumonia. The titer of serum cryptococcal antigen increased to 1:256. According to these findings, a diagnosis of primary pulmonary cryptococcosis was made, although cryptococci were neither recognized in the specimen nor cultured from the bronchial lavaged fluid. Chest radiograph showed spontaneous regression in a short period of time. However, itraconazole was administered for the prolonged cough, and the symptom disappeared. The titer of serum cryptococcal antigen decreased to 1:16 after the therapy. Pulmonary cryptococcosis should be considered as one of the differential diagnoses when chest CT scan shows combined air-space consolidation and ground-glass opacities.
机译：由于胸部射线照片显示出咳嗽和双侧斑块渗透，一名31岁的男性被送往Toranomon医院。他在入学之前很好。胸部CT扫描显示出与空气支架和相邻地面玻璃不透明的空中空间固结的斑块区域，提示支气管炎梗死组织肺炎（BOOP）。跨界肺活检标本证实了上皮细胞肉芽肿的形成，没有坏死和组织肺炎的共存。血清密集杆菌抗原的滴度增加到1：256。根据这些发现，制备了对初级肺癌皮肤病的诊断，但是既不在试样中均不识别，也不从支气管灌装液中培养。胸部射线照片在短时间内显示自发性回归。然而，伊丙康唑被延长咳嗽，症状消失。治疗后，血清密集杆菌抗原的滴度降至1:16。当胸部CT扫描显示出空气空间固结和磨砂玻璃不透明度时，应将肺部密冻细胞均视为差异诊断之一。

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