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首页> 外文期刊>藥學雜誌 >Investigation for proper use of probiotics in Nagasaki University Hospital of Medicine and Dentistry
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Investigation for proper use of probiotics in Nagasaki University Hospital of Medicine and Dentistry

机译：正当益生菌在纳卡基大学医学与牙科医院的正确使用调查

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Antimicrobial agents sometimes cause the adverse effects of diarrhea and loose stool. Antibiotic-resistant lactic acid bacteria are used to prevent these adverse effects. The bacteria are not resistant to several antimicrobial agents, although the bacterium preparations are sometimes prescribed the antimicrobial agents concomitantly. Therefore this paper reports that the minimal inhibitory concentration of three new antimicrobial agents against antibiotic-resistant lactic acid bacteria were determined using a microdilution method with cation-adjusted Mueller-Hinton broth. Furthermore, we investigated antimicrobial agents that are prescribed concomitantly with antibiotic-resistant lactic acid bacterium preparations or a clostridium butyricum preparation. The bacteria were susceptible to the three new antimicrobial agents. Approximately 50% of the bacterium preparations were prescribed alone, and 30% were prescribed concomitantly with antimicrobial agents that show antimicrobial activity against the bacteria. Consequently, we suggest that pharmacists need to confirm prescriptions and to provide more drug information on antibiotic-resistant lactic acid bacterium preparations.
机译：抗微生物剂有时会导致腹泻和宽松粪便的不利影响。抗生素抗性乳酸菌用于防止这些不利影响。细菌不抵抗几种抗微生物剂，尽管有时细菌制剂伴随着抗微生物剂。因此，本文报告说，使用用阳离子调节的ueller-hinton肉汤测定三种新的抗生素乳酸菌对抗生素乳酸菌的最小抑制浓度。此外，我们调查了伴随抗生素抗性乳酸菌制剂或蛋白质丁酸的蛋白质制剂规定的抗微生物剂。细菌易于三种新的抗微生物剂。单独规定大约50％的细菌制剂，并且伴随着对细菌的抗微生物活性的抗微生物剂伴随着30％。因此，我们建议药剂师需要确认处方并提供更多关于抗菌乳酸细菌制剂的更多药物信息。

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