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首页> 外文期刊>Allergy & clinical immunology international: official organ of the International Association of Allergology and Clinical Immunology >Avian Influenza: The Next Pandemic?
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Avian Influenza: The Next Pandemic?

机译：禽流感：下一次大流行？

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Recent WebWatch columns have dealt with zoonotic (animal-to-human) disease and the health aspects of disaster. In response to growing medical and public concern, we merge these two themes now. Only a decade ago, H5N1, a highly pathogenic strain of avian influenza A virus, was found in the blood of a domestic goose in Guangdong, China. Since then, outbreaks have occurred among farm and wild birds and even cats in a number of Southeast and Eastern Asian countries, with high-mortality transmission to humans, particularly those who have regular contact with poultry - a common part of daily life in the region of the world that chickens originally came from. More than 70 people have died since 1997, most recently in Indonesia and Turkey. As of this writing, the virus has reached bird populations beyond Far Eastern countries, as far away as central and western Europe, and cases have also been reported from Africa. Human-to-human transmission has not been established or ruled out yet. It may only be a matter of time before H5N1 evolves to have this capacity, creating a pandemic like those of 1968, 1957, and, worst of all, 1918. DMA analysis, a tool not available during those years, has been conducted on tissue samples from two 1918 victims ?one a "doughboy," or American World War I soldier, and the other an Inuit woman whose body was preserved in Arctic ice. The H5N1 strain is strikingly similar to this earlier one, H1N1. What does the threat of H5N1 mean for the global medical, veterinary, and life science communities - not to mention the general human public, domesticated animals, and wild ones? What should it mean? An important first line of defense is educating ourselves and one another about the currently known facts and possibilities, in a spirit of realistic concern, and staying updated about them. This option is available already, and the Internet can surely help us to exercise it.
机译：最近的WebWatch专栏文章讨论了人畜共患疾病（动物对人类）和灾难的健康方面。为了应对日益增长的医疗和公众关注，我们现在将这两个主题合并。仅仅十年前，在中国广东省一只家养鹅的血液中发现了高致病性的甲型禽流感病毒H5N1。从那以后，在许多东南亚和东亚国家，农作物和野生鸟类甚至猫都爆发了禽流感，这种禽流感将高死亡率传播给人类，特别是那些经常与家禽接触的人，这是该地区日常生活的一部分最初来自世界各地的鸡肉。自1997年以来，已有70多人死亡，最近的一次是在印度尼西亚和土耳其。在撰写本文时，该病毒已传播到远东国家以外，甚至中欧和西欧以外的鸟类种群，非洲也有报告病例。人与人之间的传播尚未建立或排除。 H5N1具备这种能力的发展可能只是时间问题，从而导致像1968年，1957年以及1918年最严重的大流行。DMA分析是那些年来不可用的工具，两名1918年遇难者的样本–一个是“面团小子”或美国第一次世界大战的士兵，另一个是因纽特人的妇女，尸体被保存在北极冰层中。 H5N1毒株与早期的H1N1毒株极为相似。 H5N1的威胁对全球医学，兽医和生命科学界意味着什么-更不用说普通人类，驯养的动物和野生动物了？什么意思重要的第一道防线是本着切合实际的精神，互相教育当前已知的事实和可能性，并保持最新状态。此选项已经可用，Internet肯定可以帮助我们使用它。

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