Water-based hydrogen-atom wires as mediators in long-range proton-coupled electron transfer in enzymes: A new twist on water reactivity

Cárdenas D.J.; Cuerva J.M.; Alías M.; Bu?uel E.; Campa?a A.G.

首页> 外文期刊>Chemistry: A European journal >Water-based hydrogen-atom wires as mediators in long-range proton-coupled electron transfer in enzymes: A new twist on water reactivity

【24h】

Water-based hydrogen-atom wires as mediators in long-range proton-coupled electron transfer in enzymes: A new twist on water reactivity

机译：水基氢原子线作为酶的远程质子耦合电子转移中的介质：水反应性的新扭曲

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Water is a conducting ligand between metal complexes! Water mediates the long-range proton-coupled electron transfer between two Cu complexes separated by 11? in the peptidylglycine α-hydroxylating monooxygenase (PHM) cofactor (see scheme). The proposed mechanism, which involves three H-atom exchanges, accounts for long-range electron transfer in metalloenzymes, and may be ubiquitous in nature.

机译：水是金属配合物之间的导电配体！水介导在11个分开的两个Cu复合物之间的远程质子偶联电子转移？在肽基甘氨酸α-羟化单氧化单酰基酶（PHM）辅因子（参见方案）。该提出的机制涉及三个H-原子交换，占金属酶中的远程电子转移，并且本质上可能是普遍存气的。

著录项

来源
《Chemistry: A European journal》 |2011年第30期|共6页
作者
Cárdenas D.J.; Cuerva J.M.; Alías M.; Bu?uel E.; Campa?a A.G.;
展开▼
作者单位

Departamento de Química Orgánica Universidad Aut?noma de Madrid Campus de Cantoblanco 28049-Madrid Spain;

Departamento de Química Orgánica Universidad de Granada Campus de Fuentenueva s/n 18071 Granada Spain;

Departamento de Química Orgánica Universidad de Zaragoza 50009 Zaragoza Spain;

Departamento de Química Orgánica Universidad Aut?noma de Madrid Campus de Cantoblanco 28049-Madrid Spain;

Departamento de Química Orgánica Universidad Aut?noma de Madrid Campus de Cantoblanco 28049-Madrid Spain;

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类应用化学;
关键词
density functional calculations; hydrogen transfer; metalloenzymes; molecular dynamics; water;

机译：密度函数计算;氢转移;金属酶;分子动力学;水;

相似文献

外文文献
中文文献
专利

1. Water-Based Hydrogen-Atom Wires as Mediators in Long-Range Proton-Coupled Electron Transfer in Enzymes: A New Twist on Water Reactivity [J] . Prof. Dr. Diego J. Cárdenas, Dr. Juan M. Cuerva, Dr. Miriam Alías, Chemistry - A European Journal . 2011,第30期

机译：水基氢原子线作为酶在质子耦合电子的长距离传递中的介体：对水反应性的新认识
2. The role of water-based hydrogen atom wires in long-range electron-transfer reactions in aqueous media for the fe~(II)-Fe~(III) Self-exchange and related systems [J] . Campa?a A.G., Bu?uel E., Cuerva J.M., Chemistry: A European journal . 2013,第48期

机译：水性氢原子线在水介质中Fe〜（II）-Fe〜（III）自交换及相关体系中的远距离电子转移反应中的作用
3. Oxidative Thymine Mutation in DNA: Water-Wire-Mediated Proton-Coupled Electron Transfer [J] . Robert N. Barnett, Joshy Joseph, Uzi Landman, Journal of the American Chemical Society . 2013,第10期

机译：DNA中的氧化胸腺嘧啶突变：水线介导的质子耦合电子转移。
4. A MNDO-PM5 STUDY OF THE ENZYME-FREE NADH GENERATION FROM NAD+ IN THE PRESENCE OF ELECTRON-TRANSFER MEDIATOR AND AN EVALUATION OF THE PROCESS BASED ON BACTERIAL BIOLUMINESCENCE [C] . T SUGIMOTO, N WADA, H KARATANI International Symposium on Bioluminescence and Chemiluminescence . 2005

机译：在电子转移介质存在下，从NAD +产生酶NADH生成的MNDO-PM5研究及基于细菌生物发光的过程评价
5. Proton-Coupled Electron Transfer Reactivity of Ruthenium Complexes with Separation Between the Proton and Electron Transfer Sites. [D] . Wittman, Jessica M. 2014

机译：质子与电子转移位点之间分离的钌配合物的质子耦合电子转移反应性
6. Electron proton and hydrogen-atom transfers in photosynthetic water oxidation. [O] . Cecilia Tommos 2002

机译：光合水氧化中的电子质子和氢原子转移。
7. Mechanisms for Hydrogen-Atom Abstraction by Mononuclear Copper(III) Cores: Hydrogen-Atom Transfer or Concerted Proton-Coupled Electron Transfer? [O] . -1

机译：单核铜（III）芯的氢原子抽象机制：氢原子转移或协调质子偶联电子转移？
8. Thermally-generated reactive intermediates: Trapping of the parent ferrocene-based o-quinodimethane and reactions of diradicals generated by hydrogen-atom transfers [R] . Ferguson, J. M. 1993

机译：热产生的活性中间体：母体二茂铁基邻醌二甲烷的捕获和氢原子转移产生的双自由基反应

Water-based hydrogen-atom wires as mediators in long-range proton-coupled electron transfer in enzymes: A new twist on water reactivity

摘要

著录项

相似文献

相关主题

期刊订阅