Common-path-based device for magnetomotive OCT noise reduction

Ma Zhenhe; Liu Xiaodi; Yin Bin; Zhao Yuqian; Liu Jian; Yu Yao; Wang Yi

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Common-path-based device for magnetomotive OCT noise reduction

机译：基于公共路径的磁场OCT降噪装置

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Magnetomotive optical coherence tomography (MMOCT) is a promising imaging method for noninvasive threedimensional tracking of magnetic nanoparticle (MNP) motions in target tissues or organs. The external B-field is the driving force that provides MMOCT contrast. However, B-field modulation also introduces modulation noise, thereby decreasing the quality of the MMOCT image. In this paper, a common-path-based device is designed for modulation noise reduction. The device is capable of adjusting interference distance, reference light intensity, and imaging position (X-Y translation). The sensitivity of the MMOCT is increased by similar to 20 times with the new device. Using the proposed device, the distribution of MNPs injected in zebrafish was imaged. (C) 2020 Optical Society of America

机译：磁影光相干断层扫描（MMOCT）是靶组织或器官中磁性纳米粒子（MNP）运动的非侵入性三维跟踪的有望成像方法。外部B字段是提供MMOCT对比度的驱动力。然而，B场调制还引入调制噪声，从而降低MMOCT图像的质量。在本文中，设计了一种基于公共路径的设备，用于调制降噪。该装置能够调整干涉距离，参考光强度和成像位置（X-Y翻译）。 MMOCT的敏感性增加到新设备的20次。使用所提出的装置，斑马鱼中注射的MNP的分布是成像。（c）2020美国光学学会

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来源
《Applied optics》 |2020年第5期|共7页
作者
Ma Zhenhe; Liu Xiaodi; Yin Bin; Zhao Yuqian; Liu Jian; Yu Yao; Wang Yi;
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Northeastern Univ Qinhuangdao Sch Control Engn Qinhuangdao 066004 Hebei Peoples R China;

Northeastern Univ Qinhuangdao Sch Control Engn Qinhuangdao 066004 Hebei Peoples R China;

Northeastern Univ Qinhuangdao Sch Control Engn Qinhuangdao 066004 Hebei Peoples R China;

Northeastern Univ Qinhuangdao Sch Control Engn Qinhuangdao 066004 Hebei Peoples R China;

Northeastern Univ Qinhuangdao Sch Control Engn Qinhuangdao 066004 Hebei Peoples R China;

Northeastern Univ Qinhuangdao Sch Control Engn Qinhuangdao 066004 Hebei Peoples R China;

Northeastern Univ Qinhuangdao Sch Control Engn Qinhuangdao 066004 Hebei Peoples R China;

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正文语种 eng
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Common-path-based device for magnetomotive OCT noise reduction

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