Polarization-dependent laser autofluorescence of the polycrystalline networks of blood plasma films in the task of liver pathology differentiation

Prysyazhnyuk V. P.; Ushenko Yu. A.; Dubolazov A. V.; Ushenko A. G.; Ushenko V. A.

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Polarization-dependent laser autofluorescence of the polycrystalline networks of blood plasma films in the task of liver pathology differentiation

机译：肝脏病理学分化任务中血浆膜的多晶网络的偏振依赖性激光自发荧光

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Current research presents the results of the investigation of diagnostic efficiency of laser polarization autofluorescence for the set of endogenous fluorophores of blood plasma polycrystalline films in two spectral regions (0.5-0.53 mu m and 0.63-0.67 mu m) under the excitation of laser radiation with a wavelength of 0.405 mu m. A model of generalized optical anisotropy of protein networks of blood plasma polycrystalline films is proposed for the purpose of defining laser autofluorescence processes. Both phase (linear birefringence and optical activity) and amplitude (linear and circular dichroisms) anisotropies have been considered. Interconnections between the optimal condition of probing beam polarization state and the efficiency of induction laser autofluorescence have been found. Statistical analysis of coordinate distributions of laser polarization autofluorescence intensities is suggested by means of determination of the quantitative criteria (statistical moments of the 1st-4th orders). The efficiency of laser polarization autofluorescence of polycrystalline networks in the task of differentiation of nonalcoholic fatty liver disease and chronic hepatitis of human liver has been analyzed. (C) 2016 Optical Society of America

机译：目前的研究表明，在激光辐射激发下，在两个光谱区（0.5-0.53μm和0.63-0.67μm）下，对激光偏振自发荧光诊断效率进行调查的结果波长为0.405亩。提出了一种血浆多晶膜蛋白质网络的广义光学各向异性模型，用于定义激光自发荧光过程。已经考虑了相位（线性双折射和光学活性）和幅度（线性和圆形二中间）各向异性。发现了探测光束偏振状态的最佳条件与感应激光自发荧光的互连。通过测定定量标准（第4阶序列的统计时刻）提出了激光偏振自发荧光强度坐标分布的统计分析。分析了在非酒精性脂肪肝疾病分化中的任务中的多晶网络激光偏振自发荧光的效率。（c）2016年美国光学学会

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《Applied optics》 |2016年第12期|共7页
作者
Prysyazhnyuk V. P.; Ushenko Yu. A.; Dubolazov A. V.; Ushenko A. G.; Ushenko V. A.;
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Bukovinian State Med Univ Dept Infect Dis &

Epidemiol 2 Theatral Sq Chernovtsy Ukraine;

Chernivtsi Natl Univ Correlat Opt Deptartment 2 Kotsiubynskyi St Chernovtsy Ukraine;

Chernivtsi Natl Univ Opt &

Publishing Dept 2 Kotsiubynskyi St Chernovtsy Ukraine;

Chernivtsi Natl Univ Opt &

Publishing Dept 2 Kotsiubynskyi St Chernovtsy Ukraine;

Chernivtsi Natl Univ Correlat Opt Deptartment 2 Kotsiubynskyi St Chernovtsy Ukraine;

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Polarization-dependent laser autofluorescence of the polycrystalline networks of blood plasma films in the task of liver pathology differentiation

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