Sparse aperture arrangement for periodic LED array sampling in a Fourier ptychography microscopy system

Cheng Haobo; Chen Xin; Wen Yongfu; Wang Huaying; Lie Hui

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Sparse aperture arrangement for periodic LED array sampling in a Fourier ptychography microscopy system

机译：傅立叶PTYChography显微镜系统中定期LED阵列采样的稀疏孔径装置

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In a traditional Fourier ptychography microscopy (FPM) system, multiple low-resolution (LR) intensity images have to be sequentially captured under variable illumination angles and then stitched together in the Fourier domain, which is time-consuming. This paper proposes a sparse aperture arrangement method in which the relationship between the spatial spectrum distribution and the light-emitting diodes array sampling pattern is investigated. Mathematical models of the proposed method are developed, and numerical simulations and optical experiments are demonstrated to verify its feasibility. The results show that the number of LR images could be decreased significantly without sacrificing image reconstruction quality. To the best of our knowledge, this is the first time that the sparse aperture arrangement has been exploited for FPM. The proposed method may provide new insights for improving the efficiency of the FPM platform and discovering more applications in digital pathology. (C) 2019 Optical Society of America

机译：在传统的傅里叶PTYChography显微镜（FPM）系统中，必须在可变照明角度下依次捕获多个低分辨率（LR）强度图像，然后在傅立叶域中缝合在耗时的情况下。本文提出了一种稀疏的孔径布置方法，其中研究了空间谱分布与发光二极管阵列采样模式之间的关系。开发了所提出的方法的数学模型，并证明了数值模拟和光学实验以验证其可行性。结果表明，在不牺牲图像重建质量的情况下，可以显着降低LR图像的数量。据我们所知，这是第一次为FPM开发了稀疏的孔径安排。该方法可以为提高FPM平台的效率并在数字病理学中发现更多应用程序来提供新的见解。（c）2019年光学学会

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来源
《Applied optics》 |2019年第32期|共11页
作者
Cheng Haobo; Chen Xin; Wen Yongfu; Wang Huaying; Lie Hui;
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作者单位

Beijing Inst Technol Sch Opt &

Photon Joint Res Ctr Optomechatron Engn Beijing 10081 Peoples R China;

Beijing Inst Technol Sch Opt &

Photon Joint Res Ctr Optomechatron Engn Beijing 10081 Peoples R China;

Beijing Inst Technol Sch Opt &

Photon Joint Res Ctr Optomechatron Engn Beijing 10081 Peoples R China;

Hebei Univ Engn Sch Math &

Phys Handan 056038 Hebei Peoples R China;

Beijing Inst Technol Shenzhen Res Inst Shenzhen 518057 Peoples R China;

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Sparse aperture arrangement for periodic LED array sampling in a Fourier ptychography microscopy system

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