Visualization and label-free quantification of microfluidic mixing using quantitative phase imaging

Park GwangSik; Han Dongsik; Kim GwangSu; Shin Seungwoo; Kim Kyoohyun; Park Je-Kyun; Park YongKeun

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Visualization and label-free quantification of microfluidic mixing using quantitative phase imaging

机译：使用定量相成像进行可视化和无标记式的微流体混合的定量

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Microfluidic mixing plays a key role in various fields, including biomedicine and chemical engineering. To date, although various approaches for imaging microfluidic mixing have been proposed, they provide only quantitative imaging capability and require exogenous labeling agents. Quantitative phase imaging techniques, however, circumvent these problems and offer label-free quantitative information about concentration maps of microfluidic mixing. We present the quantitative phase imaging of microfluidic mixing in various types of polydimethylsiloxane microfluidic channels with different geometries; the feasibility of the present method was validated by comparing it with the results obtained by theoretical calculation based on Fick's law. (C) 2017 Optical Society of America

机译：微流体混合在各种领域起着关键作用，包括生物医学和化学工程。迄今为止，尽管已经提出了用于成像微流体混合的各种方法，但它们仅提供定量的成像能力并且需要外源标记剂。然而，定量相位成像技术规避了这些问题，并提供了关于微流体混合浓度图的无标签的定量信息。我们以不同几何形状的各种聚二甲基硅氧烷微流体通道的微流体混合的定量相成像; 通过将其与基于Fick律法的理论计算获得的结果进行比较，验证了本方法的可行性。（c）2017年光学学会

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来源
《Applied optics》 |2017年第22期|共7页
作者
Park GwangSik; Han Dongsik; Kim GwangSu; Shin Seungwoo; Kim Kyoohyun; Park Je-Kyun; Park YongKeun;
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Korea Adv Inst Sci &

Technol Dept Phys Daejeon 34141 South Korea;

Korea Adv Inst Sci &

Technol Dept Bio &

Brain Engn Daejeon 34141 South Korea;

Korea Adv Inst Sci &

Technol Dept Phys Daejeon 34141 South Korea;

Korea Adv Inst Sci &

Technol Dept Phys Daejeon 34141 South Korea;

Korea Adv Inst Sci &

Technol Dept Phys Daejeon 34141 South Korea;

Korea Adv Inst Sci &

Technol Dept Bio &

Brain Engn Daejeon 34141 South Korea;

Korea Adv Inst Sci &

Technol Dept Phys Daejeon 34141 South Korea;

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正文语种 eng
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Visualization and label-free quantification of microfluidic mixing using quantitative phase imaging

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