A mitochondria-targeted dual-functional aggregation-induced emission luminogen for intracellular mitochondrial imaging and photodynamic therapy

Zhang Yujie; Huang Wendi; Tan Xueying; Wang Jinhui; Zhao Yufen; Hu Jingbo; Wang Shuanghu

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A mitochondria-targeted dual-functional aggregation-induced emission luminogen for intracellular mitochondrial imaging and photodynamic therapy

机译：用于细胞内线粒体成像和光动力疗法的线粒体靶向双功能聚集诱导的排放式发光引发

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摘要

A mitochondria-targeted dual-functional aggregation-induced emission luminogen, TPP-TPEDCH, was rationally designed and developed for intracellular mitochondrial imaging and photodynamic therapy. TPP-TPEDCH clearly showed the movements of mitochondria at various time points. Moreover, both in vitro and in vivo results demonstrated its excellent ROS generation ability and strong antitumor activity.

机译：针对细胞内线粒体成像和光动力疗法合理地设计和开发了一种线粒体靶向的双功能聚集诱导的发射光荧光剂。 TPP-TPETCH在各种时间点清楚地显示了线粒体的运动。此外，体外和体内结果表明其优异的ROS生成能力和强烈的抗肿瘤活性。

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来源
《Biomaterials Science》 |2021年第4期|共5页
作者
Zhang Yujie; Huang Wendi; Tan Xueying; Wang Jinhui; Zhao Yufen; Hu Jingbo; Wang Shuanghu;
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作者单位

Ningbo Univ Fac Mat Sci &

Chem Engn Ningbo 315211 Peoples R China;

Ningbo Univ Fac Mat Sci &

Chem Engn Ningbo 315211 Peoples R China;

Zhejiang Pharmaceut Coll Coll Pharm Ningbo 315000 Peoples R China;

Ningbo Univ Inst Drug Discovery Technol Ningbo 315000 Zhejiang Peoples R China;

Ningbo Univ Inst Drug Discovery Technol Ningbo 315000 Zhejiang Peoples R China;

Ningbo Univ Fac Mat Sci &

Chem Engn Ningbo 315211 Peoples R China;

Wenzhou Med Univ Lab Clin Pharm Peoples Hosp Lishui Affiliated Hosp 6 Lishui 323000 Peoples R China;

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正文语种 eng
中图分类分子生物学;
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2. Aggregation-induced emission luminogen-assisted stimulated emission depletion nanoscopy for super-resolution mitochondrial visualization in live cells [J] . Dongyu Li, Xiang Ni, Xiaoyan Zhang, 纳米研究（英文版） . 2018,第011期
3. Aggregation-induced emission luminogen-assisted stimulated emission depletion nanoscopy for super-resolution mitochondrial visualization in live cells [J] . Dongyu Li1, Xiang Ni2, Xiaoyan Zhang2, 纳米研究：英文版 . 2018,第011期
4. Aggregation-Induced Emission Luminogens with the Capability of Wide Color Tuning, Mitochondrial and Bacterial Imaging, and Photodynamic Anticancer and Antibacterial Therapy [J] . Zhao Na, Li Pengfei, Zhuang Jiabao, ACS applied materials & interfaces . 2019,第12期

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5. Image-guided combination chemotherapy and photodynamic therapy using a mitochondria-targeted molecular probe with aggregation-induced emission characteristics [J] . Zhang Chong-Jing, Hu Qinglian, Feng Guangxue, Chemical science . 2015,第8期

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7. Overcoming chemoresistance using tumor mitochondria-targeted photodynamic therapy [C] . Yang Liu, Jing Cui, Meng Su, Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XXVIII . 2019

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A mitochondria-targeted dual-functional aggregation-induced emission luminogen for intracellular mitochondrial imaging and photodynamic therapy

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