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首页> 外文期刊>British journal of ophthalmology >Repeatability of swept-source optical coherence tomography retinal and choroidal thickness measurements in neovascular age-related macular degeneration
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Repeatability of swept-source optical coherence tomography retinal and choroidal thickness measurements in neovascular age-related macular degeneration

机译：扫掠光学相干断层扫描视网膜和脉络膜厚度测量的可重复性与新血管时期相关的黄斑变性

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Background The aim was to determine the intrasession repeatability of swept-source optical coherence tomography (SS-OCT)-derived retinal and choroidal thickness measurements in eyes with neovascular age-related macular degeneration (nAMD). Methods A prospective study consisting of patients with active nAMD enrolled in the Distance of Choroid Study at Moorfields Eye Hospital, London. Patients underwent three 12x9 mm macular raster scans using the deep range imaging (DRI) OCT-1 SS-OCT (Topcon) device in a single imaging session. Retinal and choroida! thicknesses were calculated for the ETDRS macular subfields. Repeatability was calculated according to methods described by Bland and Altman. Results 39 eyes of 39 patients with nAMD were included with a mean (盨D) age of 73.9 (?.2) years. The mean (盨D) retinal thickness of the central macular subfield was 225.7 糾 (?2.4 糾). The repeatability this subfield, expressed as a percentage of the mean central macular subfield thickness, was 23.2%. The percentage repeatability of the other macular subfields ranged from 13.2% to 28.7%. The intrasession coefficient of repeatability of choroidal thickness of the centra! macular subfield was 57.2 糾 with a mean choroidal thickness (盨D) of 181 糾 (?5.8 糾). Conclusions This study suggests that a change >23.2% of retinal thickness and 57.2um choroidal thickness in the central macular subfield is required to distinguish true clinical change from measurement variability when using the DRI OCT-1 device to manage patients with nAMD.
机译：背景技术目的是确定扫描源光学相干断层扫描（SS-OCT）的渗透可重复性（SS-OCT）的视网膜和脉络膜厚度测量与新生血管年龄相关的黄斑变性（NAMD）。方法采用活跃NAMD患者的前瞻性研究，伦敦摩尔菲尔德眼科医院的脉络膜研究距离。在单个成像会话中使用深度成像（DRI）OCT-1 SS-OCT（TOPCON）设备进行三个12x9 mm黄斑栅的扫描。视网膜和choroida！为ETDRS黄斑子场计算厚度。根据Bland和Altman描述的方法计算重复性。结果39例NAMD患者的39只眼睛包括在73.9岁（？.2）年龄的平均值（盨D）。中央黄斑子场的平均值（χd）视网膜厚度为225.7‰（？2.4‰）。这种子场的重复性表示为平均中央黄斑厚度的百分比为23.2％。另一个黄斑亚场的可重复性范围为13.2％至28.7％。 Centra的脉络膜厚度的杂交系数！黄斑子场为57.2‰，平均脉络膜厚度（χd）为181‰（？5.8‰）。结论本研究表明，在使用DRI OCT-1设备管理NAMD患者时，需要在中央黄斑厚度和57.2um脉络膜厚度中的变化> 23.2％的视网膜厚度和57.2um脉络膜厚度。

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