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首页> 外文期刊>Best practice & research:Clinical obstetrics & gynaecology >Assisted conception in women of advanced maternal age
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Assisted conception in women of advanced maternal age

机译：促进孕产妇年龄的妇女辅助观念

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A delay in childbearing to later in life has increased the number of women of advanced maternal age (AMA) opting for assisted reproduction. Women should be made aware that there are age-related changes to fertility, including a decline in oocyte reserve and quality, in addition to an increase in the number of oocyte chromosomal aberrations. Success rates of assisted reproductive technology (ART) cycles decrease with advanced maternal age. There are different fertility options for women of AMA, including fertility preservation (oocyte or embryo freezing), in vitro fertilisation (IVF treatment) with or without preimplantation genetic screening and oocyte or embryo donation. Detailed counselling needs to be offered to these women with regard to the risks, success rates, ethical and legal implications of these fertility treatment options. Women of AMA should be screened for underlying medical conditions that could have an impact on maternal and neonatal morbidity and mortality. (C) 2020 Published by Elsevier Ltd.
机译：生育推迟到晚年增加了选择辅助生育的高龄产妇人数。应该让女性意识到，生育能力存在与年龄相关的变化，包括卵母细胞储备和质量的下降，以及卵母细胞染色体畸变数量的增加。辅助生殖技术（ART）周期的成功率随着母亲年龄的增加而降低。AMA女性有不同的生育选择，包括保留生育能力（卵母细胞或胚胎冷冻）、体外受精（IVF治疗），无论是否进行植入前基因筛查，以及卵母细胞或胚胎捐献。需要就这些生育治疗方案的风险、成功率、伦理和法律影响向这些妇女提供详细的咨询。AMA妇女应接受筛查，以了解可能影响孕产妇和新生儿发病率和死亡率的潜在医疗状况。（C） 2020年爱思唯尔有限公司出版。

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