SETting Up for Epigenetic Regulation of Advanced Prostate Cancer

Thienger Phillip; Rubin Mark A.

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SETting Up for Epigenetic Regulation of Advanced Prostate Cancer

机译：建立晚期前列腺癌的表观遗传调控

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An outgrowth of therapy-resistant prostate cancers (PCa) with enhanced metastatic potential may be triggered by inhibitors of androgen receptor (AR) signaling, often via epigenetic rewiring. In this issue of Cancer Cell, Yuan et al. demonstrate how SETD2 integrates EZH2 and AMPK signaling pathways to keep PCa metastasis in check.

机译：雄激素受体（AR）信号抑制剂可能会引发转移潜能增强的治疗耐受性前列腺癌（PCa）的生长，通常是通过表观遗传重组。在本期《癌细胞》中，袁等人展示了SETD2如何整合EZH2和AMPK信号通路，以控制PCa的转移。

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《Cancer Cell》 |2020年第3期|共3页
作者
Thienger Phillip; Rubin Mark A.;
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Univ Bern Dept BioMed Res Bern Switzerland;

Univ Bern Dept BioMed Res Bern Switzerland;

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正文语种 eng
中图分类肿瘤学;
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1. Specific changes in the expression of imprinted genes in prostate cancer-implications for cancer progression and epigenetic regulation [J] . Teodora Ribarska, Klaus-Marius Bastian, Annemarie Koch, 亚洲男性学杂志（英文版） . 2012,第003期
2. Epigenetic regulation of prostate cancer:the theories and the clinical implications [J] . Yiji Liao, Kexin Xu 亚洲男性学杂志（英文版） . 2019,第003期
3. Perioperative complications of radical retropubic prostatectomy in patients with locally advanced prostate cancer: a comparison with clinically localized prostate cancer [J] . Xu-Dong Yao, Xiao-Jun Liu, Shi-Lin Zhang, 亚洲男性学杂志（英文版） . 2013,第002期
4. Serum prostate-specific antigen value adjusted for non-cancerous prostate tissue volume in patients undergoing radical prostatectomy： a new predictor of biochemical recurrence in localized or locally advanced prostate cancer [J] . Ja Hyeon Ku, Kyung Chul Moon, Sung Yong Cho, 亚洲男性学杂志：英文版 . 2011,第002期
5. Epigenetic modulations and lineage plasticity in advanced prostate cancer [J] . Annals of oncology: official journal of the European Society for Medical Oncology . 2020,第4期

机译：表观遗传调制和晚期前列腺癌中的谱系可塑性
6. Combinatorial strategy of epigenetic and hormonal therapies: A novel promising approach for treating advanced prostate cancer [J] . Motawi Tarek K., Darwish Hebatallah A., Diab Iman, Life sciences . 2018,第期

机译：表观遗传和激素疗法的组合策略：一种治疗晚期前列腺癌的新颖途径
7. Identification of the epigenetic reader CBX2 as a potential drug target in advanced prostate cancer [J] . Pier-Luc Clermont, Francesco Crea, Yan Ting Chiang, Clinical epigenetics. . 2016,第1期

机译：表观遗传阅读器CBX2鉴定为晚期前列腺癌的潜在药物靶标
8. Epigenetic Regulation of Normal and Cancer Stem Cells [C] . MICHAEL F. CLARKE International Conference and Workshop on Hematopoietic Stem Cells . 2005

机译：正常和癌症干细胞的表观遗传调节
9. Epigenetic regulation of apoptosis in prostate cancer. [D] . Zhang, Qunshu. 2015

机译：前列腺癌凋亡的表观遗传学调控。
10. Specific changes in the expression of imprinted genes in prostate cancer—implications for cancer progression and epigenetic regulation [O] . Teodora Ribarska, Klaus-Marius Bastian, Annemarie Koch, 2012

机译：前列腺癌印迹基因表达的特定变化-对癌症进展和表观遗传调控的启示
11. Identification of the epigenetic reader CBX2 as a potential drug target in advanced prostate cancer [O] . Clermont Pier-Luc, Crea Francesco, Chiang Yan Ting, 2016

机译：鉴定表观遗传学读取器CBX2作为晚期前列腺癌的潜在药物靶标
12. Epigenetic Regulation of Chermokine Expression in Prostate Cancer [R] . Shurin, M. R. 2008

机译：前列腺癌中Chermokine表达的表观遗传调控

SETting Up for Epigenetic Regulation of Advanced Prostate Cancer

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