One or Two Immune Checkpoint Inhibitors?

Robert Caroline; Lanoy Emilie; Besse Benjamin

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One or Two Immune Checkpoint Inhibitors?

机译：一个或两个免疫检查点抑制剂？

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The combination of ipilimumab and nivolumab was evaluated versus standard treatments in melanoma and lung cancer. Analysis of these trials highlights the differences in outcomes and potential predictive biomarkers across tumor types as well as the multiple remaining questions concerning the optimal use of immune checkpoint inhibitors.

机译：对比黑色素瘤和肺癌的标准治疗，对伊普利单抗和nivolumab的联合治疗进行评估。对这些试验的分析强调了不同肿瘤类型的结果和潜在预测性生物标志物的差异，以及关于免疫检查点抑制剂最佳使用的多个剩余问题。

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来源
《Cancer Cell》 |2019年第6期|共4页
作者
Robert Caroline; Lanoy Emilie; Besse Benjamin;
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作者单位

Gustave Roussy Canc Campus Dept Canc Med 114 Rue Edouard Vaillant F-94805 Villejuif France;

Gustave Roussy Canc Campus Biostat &

Epidemiol Unit 114 Rue Edouard Vaillant F-94805 Villejuif;

Gustave Roussy Canc Campus Dept Canc Med 114 Rue Edouard Vaillant F-94805 Villejuif France;

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原文格式 PDF
正文语种 eng
中图分类肿瘤学;
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1. Association of baseline peripheral-blood eosinophil count with immune checkpoint inhibitor-related pneumonitis and clinical outcomes in patients with non-small cell lung cancer receiving immune checkpoint inhibitors (vol 150, pg 76, 2020) [J] . Chu Xiangling, Zhao Jing, Zhou Juan, Lung cancer: Journal of the International Association for the Study of Lung Cancer . 2021,第1期

机译：基线外周血嗜酸性粒细胞计数与免疫检查点抑制剂相关的肺炎和非小细胞肺癌接受免疫检查点抑制剂患者的临床结果（Vol 150，PG 76,2020）
2. Are immune checkpoint combination therapies for intermediate and poor risk renal cell carcinoma better than immune checkpoint inhibitors combined with kinase inhibitors? [J] . McDermott David F., Atkins Michael B. The lancet oncology . 2021,第5期

机译：免疫检查点组合治疗中间体和差的风险肾细胞癌优于免疫检查点抑制剂与激酶抑制剂合并吗？
3. Re: Keiichiro Mori, Mohammad Abufaraj, Hadi Mostafaei, et al. The Predictive Value of Programmed Death Ligand 1 in Patients with Metastatic Renal Cell Carcinoma Treated with Immune-checkpoint Inhibitors: A Systematic Review and Meta-analysis. Eur Urol. In press. https://doi.org/10.1016/j.eururo.2020.10.006 Clinical Activity of Immune Checkpoint Inhibitors: Is the Host the Answer? [J] . Noel Johanna, Huillard Olivier, Goldwasser Francois European urology . 2021,第4期

机译：Re：Keiichiro Mori，Mohammad Abufaraj，Hadi Mostafaei，等。用免疫检查点抑制剂治疗的转移性肾细胞癌患者编程死亡配体1的预测值：系统评价和荟萃分析。 EUR UROL。在新闻。 https://doi.org/10.1016/j.eururo.2020.10.006免疫检查点抑制剂的临床活动：主持人答案是什么？
4. ENGINEERING AND PRE-CLINICAL EVALUATION OF A HUMAN ENZYME IMMUNE CHECKPOINT INHIBITOR FOR CANCER THERAPY [C] . Everett Stone, John Blazek, Christos Karamitros, Enzyme Engineering Conference . 2018

机译：癌症治疗人酶免疫检查点抑制剂的工程与临床评价
5. Immune-Related Adverse Events in Cancer Patients Being Treated with Immune Checkpoint Inhibitors [D] . Byrne, Margaret M. 2021

机译：用免疫检查点抑制剂治疗癌症患者免疫相关不良事件
6. Comparison of a combination of chemotherapy and immune checkpoint inhibitors and immune checkpoint inhibitors alone for the treatment of advanced and metastatic non‐small cell lung cancer [O] . Chih‐Hsi Scott Kuo, Chin‐Chou Wang, Yu‐Chen Huang, 2019

机译：比较化学疗法和免疫检查点抑制剂以及单独的免疫检查点抑制剂联合治疗晚期和转移性非小细胞肺癌的比较
7. Association of baseline peripheral-blood eosinophil count with immune checkpoint inhibitor-related pneumonitis and clinical outcomes in patients with non-small cell lung cancer receiving immune checkpoint inhibitors [O] . Xiangling Chu, Jing Zhao, Juan Zhou, 2020

机译：基线外周血嗜酸性粒细胞计数与免疫检查点抑制剂相关的肺炎和非小细胞肺癌接受免疫检查点抑制剂患者的临床结果
8. Phase 1 Trial of an Immune Checkpoint Inhibitor plus Stereotactic Ablative Radiotherapy in Patients with Inoperable Stage I Non-Small Cell Lung Cancer. [R] . Kelly, K., Monjazeb, A., Daly, M., 2017

机译：免疫检查点抑制剂加立体定向消融放疗治疗不能手术的I期非小细胞肺癌的1期试验。

One or Two Immune Checkpoint Inhibitors?

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