Break on Through: Golgi-Derived Vesicles Aid in Mitochondrial Fission

Rasmussen Megan L.; Robertson Gabriella L.; Gama Vivian

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Break on Through: Golgi-Derived Vesicles Aid in Mitochondrial Fission

机译：通过：Golgi衍生的囊泡助剂在线粒体裂变中

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Mitochondrial fission is sustained through contact with several organelles, including the endoplasmic reticulum, lysosomes, and the actin cytoskeleton. Nagashima et al. (2020) now demonstrate that PI(4)P-containing Golgi-derived vesicles also modulate mitochondrial fission, driven by Arf1 and PI(4)KIII beta activity, identifying a new organelle contact involved in maintaining mitochondrial homeostasis.

机译：线粒体分裂是通过与几种细胞器的接触来维持的，包括内质网、溶酶体和肌动蛋白细胞骨架。Nagashima等人（2020年）现在证明，在Arf1和PI（4）KIIIβ活性的驱动下，含PI（4）P的高尔基体衍生囊泡也会调节线粒体分裂，从而识别出一种参与维持线粒体内环境稳定的新细胞器接触。

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《Cell metabolism》 |2020年第6期|共3页
作者
Rasmussen Megan L.; Robertson Gabriella L.; Gama Vivian;
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Vanderbilt Univ Dept Cell &

Dev Biol 221 Kirkland Hall Nashville TN 37235 USA;

Vanderbilt Univ Dept Cell &

Dev Biol 221 Kirkland Hall Nashville TN 37235 USA;

Vanderbilt Univ Dept Cell &

Dev Biol 221 Kirkland Hall Nashville TN 37235 USA;

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正文语种 eng
中图分类内分泌腺疾病及代谢病;
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1. Porphyromonas gingivalis infection promotes mitochondrial dysfunction through Drp1-dependent mitochondrial fission in endothelial cells [J] . Tong Xu, Qin Dong, Yuxiao Luo, 国际口腔科学杂志（英文版） . 2021,第003期
2. 4-49 Inhibiting Mitochondrial Fission Changed the Mitochondrial Responses in MDA-MB-231 Cells after Carbon Ion Irradiation [J] . Jin Xiaodong, Li Feifei, Liu Bingtao, 中国科学院近代物理研究所和兰州重离子研究装置年报：英文版 . 2016,第001期
3. A Golgi-derived vesicle potentiates PtdIns4P to PtdIns3P conversion for endosome fission [J] . Gong Bo, Guo Yuting, Ding Shihui, Nature cell biology . 2021,第7期

机译：一种衍生的囊泡增强PTDINS4P至PTDINS3P转化用于内体裂变
4. Golgi-derived PI(4)P-containing vesicles drive late steps of mitochondrial division [J] . Nagashima Shun, Tabara Luis-Carlos, Tilokani Lisa, Science . 2020,第6484期

机译：Golgi衍生的PI（4）含P的囊泡驱动线粒体划分的后期步骤
5. Sharpening the scissors: mitochondrial fission with aid. [J] . Yoon Y Cell biochemistry and biophysics . 2004,第2期

机译：削尖剪刀：借助辅助线粒体裂变。
6. MITOCHONDRIOTROPIC VESICLES DELIVER MITOCHONDRIAL LEADER PEPTIDECONJUGATES OF CIRCULAR AND LINEAR DOUBLE STRANDED DNA INTO MAMMALIANMITOCHONDRIA [C] . G.G.M. DSouza, S. V. Boddapati, R.N. Lightowlers, Annual meeting exposition of the Controlled Release Society . 2005

机译：线粒体血管将线粒体和线形双链DNA的线粒体领先者肽结合物转运至哺乳动物线粒体中
7. Roles of Macrophage Mitochondrial Oxidative Stress and Mitochondrial Fission in Atherosclerosis. [D] . Wang, Ying. 2014

机译：巨噬细胞线粒体氧化应激和线粒体裂变在动脉粥样硬化中的作用。
8. Mesenchymal Stromal Cells Derived Extracellular Vesicles Ameliorate Acute Renal Ischemia Reperfusion Injury by Inhibition of Mitochondrial Fission through miR-30 [O] . Di Gu, Xiangyu Zou, Guanqun Ju, 2016

机译：间充质基质细胞衍生的细胞外液通过抑制线粒体裂变通过miR-30改善急性肾缺血再灌注损伤。
9. Regulation of Glucose-Dependent Golgi-Derived Microtubules by cAMP/EPAC2 Promotes Secretory Vesicle Biogenesis in Pancreatic β Cells [O] . Kathryn P. Trogden, Xiaodong Zhu, Justin S. Lee, 2019

机译：CAMP / EPAC2调节葡萄糖依赖性的GOLGI衍生的微管促进胰腺β细胞中的分泌囊泡生物发生
10. Influence of Cycloheximide and 1,25-Dihydroxy-vitamin D3 on Mitochondrial and Vesicle Mineralization in the Intestine. [R] . Morrissey, R. L., Zolock, D. T., Mellick, P. W., 1979

机译：环己酰亚胺和1,25-二羟基维生素D3对肠道线粒体和囊泡矿化的影响。

Break on Through: Golgi-Derived Vesicles Aid in Mitochondrial Fission

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