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首页> 外文期刊>Cellular and molecular biology >Delayed development influences the outcome of different grades of D5 and D6 blastocysts during freeze-thaw cycle
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Delayed development influences the outcome of different grades of D5 and D6 blastocysts during freeze-thaw cycle

机译：延迟的发展在冻融周期中影响了不同等级的D5和D6胚泡的结果

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摘要

To analyze the effects of blastocysts on the 5th day (D5) and 6th day (D6) of frozen-thawed blastocyst transplantation on pregnancy outcome and provide evidence for further improvement of the strategy. This study included transfers from the Reproductive Medicine Center of the Second Affiliated Hospital of Wenzhou Medical University during freeze-thaw cycles from January 2016 to December 2017. They were divided into D5 group (1616 cases) and D6 group (619 cases) according to blastocyst formation and development. Each group was further divided into 5 groups according to the quality of the blastocyst and the number of transplants, making a total of 10 groups. Following the frozen transplantation cycle, the transplanting rate was significantly higher for D5 (41.73%) than for D6 (23.98%) (P < 0.05); the ongoing pregnancy rate (47,40%) was also significantly higher than that of D6 (28.43%) (P < 0.05). In the frozen-thawed blastocyst resuscitation transplantation, compared to D6 blastocysts, D5 blastocysts were more conducive to blastocyst implantation and could be used to achieve better clinical pregnancy outcome. In blastocyst selection, a single D5 excellent blastocyst transplant is preferred. Only at the 6th day of non-excellent D6, 2 blastocysts are recommended for transplantation.
机译：分析冻融囊胚移植第5天（D5）和第6天（D6）囊胚对妊娠结局的影响，为进一步改进策略提供依据。本研究包括2016年1月至2017年12月冻融循环期间温州医科大学第二附属医院生殖医学中心的转移。根据囊胚的形成和发育情况分为D5组（1616例）和D6组（619例）。根据囊胚质量和移植数量，每组又分为5组，共10组。在冷冻移植周期后，D5的移植率（41.73%）显著高于D6（23.98%）（P<0.05）；继续妊娠率（47,40%）也显著高于D6组（28.43%）（P<0.05）。在冻融胚泡复苏移植中，与D6胚泡相比，D5胚泡更有利于胚泡着床，可用于获得更好的临床妊娠结局。在选择胚泡时，最好是进行单个D5优质胚泡移植。仅在非优D6的第6天，建议移植2个囊胚。

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