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首页> 外文期刊>Cardiovascular engineering and technology >Proper Orthogonal Decomposition Analysis of the Flow Downstream of a Dysfunctional Bileaflet Mechanical Aortic Valve
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Proper Orthogonal Decomposition Analysis of the Flow Downstream of a Dysfunctional Bileaflet Mechanical Aortic Valve

机译：适当的正交分解分析功能障碍双面机械主动脉瓣下游的流动

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Purpose—Aortic valve replacement remains the only viable solution for symptomatic patients with severe aortic valve stenosis. Despite their improved design and long history of successful operation, bileaflet mechanical heart valves are still associated with post-operative complications leading to valve dysfunction. Thus, the flow dynamics can be highly disturbed downstream of the dysfunctional valve. Methods—In this in vitro study, the flow dynamics downstream of healthy and dysfunctional bileaflet mechanical heart valves have been investigated using particle image velocimetry measurements. Proper orthogonal decomposition of the velocity field has been performed in order to explore the coherent flow features in the ascending aorta in the presence of a dysfunctional bileaflet mechanical heart valve. Results—The ability of proper orthogonal decomposition derived metrics to differentiate between heathy and dysfunctional cases is reported. Moreover, reduced-order modeling using proper orthogonal decomposition is thoroughly investigated not only for the velocity field but also for higher order flow characteristics such as time average wall shear stress, oscillatory shear index and viscous energy dissipation. Conclusion—Considering these results, proper orthogonal decomposition can provide a rapid binary classifier to evaluate if the bileaflet mechanical valve deviates from its normal operating conditions. Moreover, the study shows that the size of the reduced-order model depends on which flow parameter is required to be reconstructed.
机译：目的主动脉瓣置换术仍然是严重主动脉瓣狭窄症状患者唯一可行的解决方案。尽管双叶机械心脏瓣膜的设计得到了改进，并且有着长期的成功手术史，但它们仍然与导致瓣膜功能障碍的术后并发症有关。因此，功能失调的阀门下游的流体动力学可能会受到严重干扰。方法在体外研究中，使用粒子图像测速仪测量健康和功能失调的双叶机械心脏瓣膜下游的流动动力学。对速度场进行了适当的正交分解，以探索在存在功能失调的双叶机械心脏瓣膜的情况下升主动脉中的相干流动特征。结果报道了适当正交分解衍生指标区分健康和功能障碍病例的能力。此外，采用适当正交分解的降阶模型不仅适用于速度场，而且适用于高阶流动特性，如时间平均壁面剪应力、振荡剪切指数和粘性能量耗散。结论考虑到这些结果，适当的正交分解可以提供一个快速的二元分类器来评估双叶机械瓣膜是否偏离其正常工作条件。此外，研究表明，降阶模型的大小取决于需要重构的流动参数。

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