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Physical, mechanical, and in vitro biological analysis of bioactive fibers-based dental composite

机译:生物活性纤维牙科复合材料的物理,机械和体外生物学分析

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摘要

This study aimed to synthesize experimental composites reinforced with various concentrations (0, 40, 50, and 60 wt%) of nano-hydroxyapatite grafted glass fibers. The release of monomers, residual monomers, and in-vitro bioactivity of composite groups were evaluated after 1, 7, and 28 days. Compressive strength/ modulus, cell viability (by direct and indirect method), and bacterial adhesion were evaluated. The results showed that bis-GMA was released from all samples. TEGDMA released from 50 and 60 wt% samples on day 1 and UDMA showed negligible release. Compressive strength values of 40 wt% sample were higher than other experimental groups. New apatite layer was formed, whereby both direct and indirect methods demonstrated cell viability. The numbers of active colonies grown were least for 60 wt% sample while their number increased over time. The nano-hydroxyapatite/glass fibers have potential to be used as filler in dental composites and experimental composites were found to be biocompatible and comparable with commercial material.
机译:本研究旨在合成不同浓度(0、40、50和60 wt%)纳米羟基磷灰石接枝玻璃纤维增强的实验复合材料。在1、7和28天后评估单体的释放、残余单体和复合组的体外生物活性。评估抗压强度/模量、细胞活力(通过直接和间接方法)和细菌粘附。结果表明,所有样品均释放出bis-GMA。TEGDMA在第1天从50%和60%的样品中释放,UDMA的释放可忽略不计。40%试样的抗压强度值高于其他实验组。新的磷灰石层形成,直接和间接的方法都证明了细胞的活力。在60 wt%的样品中,生长的活性菌落数量最少,而它们的数量随着时间的推移而增加。纳米羟基磷灰石/玻璃纤维有潜力用作牙科复合材料的填料,实验发现复合材料具有生物相容性,与商业材料相当。

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