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Electroactive interpenetrated biohydrogels as hybrid materials based on conducting polymers

机译:电活性渗透性生物氢化合物作为基于导电聚合物的混合材料

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摘要

Different levels of interpenetration of poly(hydroxymethyl-3,4-ethylenedioxythiophene) (PHMeDOT) inside a poly-gamma-glutamic acid (gamma PGA) biohydrogel matrix, previously loaded with microparticles of poly(3,4-ethylenedioxythiophene) (PEDOT), have been obtained. The degree of interpenetration has shown influence on the morphological and electrochemical properties of the resulting biohydrogel ([PEDOT/gamma PGA]PHMeDOT) with a maximum after 1 h of PHMeDOT polymerization time. The high biocompatibility of all biohydrogel components, together with the combination of mechanical properties of gamma PGA hydrogels with the electrochemical properties of interconnected microparticles of PEDOT, makes it a promising material for next generation of biosensors.
机译:已经获得了聚(羟甲基-3,4-亚乙基二氧噻吩)(PHMeDOT)在先前装载有聚(3,4-亚乙基二氧噻吩)(PEDOT)微粒的聚γ-谷氨酸(γ-PGA)生物水凝胶基质内的不同程度的互穿。互穿程度已显示出对所得生物水凝胶([PEDOT/gamma PGA]pMedot)的形态和电化学性质的影响,在pMedot聚合时间1小时后达到最大值。所有生物水凝胶组件的高度生物相容性,加上伽马PGA水凝胶的机械性能与PEDOT相互连接的微粒的电化学性能的结合,使其成为下一代生物传感器的有希望的材料。

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