• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of Applied Polymer Science >Different real-time degradation scenarios of functionalized poly(epsilon-caprolactone) for biomedical applications
【24h】

Different real-time degradation scenarios of functionalized poly(epsilon-caprolactone) for biomedical applications

机译：用于生物医学应用的官能化聚（ε-己内酯）的不同实时降解场景

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Anterior cruciate ligament (ACL) ruptures are a much-commented injury as it can end the season or even career of professional athletes. However, the recovery of a patient from the general population is no less painful during the long period required by current treatments. Artificial ligaments could improve this healing, yet, orthopedic surgeons are still cautious about permanent ACL implants. Therefore, combining biodegradation and bioactivity could be a key feature for the popularization of these devices. This study aim at evaluating the real-time degradation of poly(epsilon-caprolactone) (PCL) grafted with the bioactive polymer sodium polystyrene sulfonate in different scenarios. PCL physical-chemical properties were evaluated before and after degradation. In addition, in vitro experiments were realized to confirm the long term influence of the grafting on cell response. Altogether, we were able to show different degradations scenarios, enabling to study the impact of degradation environment on degradation mode and rate of functionalized PCL.
机译：前交叉韧带（ACL）断裂是一种备受关注的损伤，因为它可能会结束职业运动员的赛季甚至职业生涯。然而，在当前治疗所需的长时间内，患者从普通人群中恢复过来的痛苦并没有减少。人工韧带可以改善这种愈合，然而，骨科医生对永久性ACL植入仍持谨慎态度。因此，将生物降解和生物活性结合起来可能是这些设备普及的关键特征。本研究旨在评估生物活性聚合物聚苯乙烯磺酸钠接枝的聚己内酯（PCL）在不同情况下的实时降解。降解前后对PCL的理化性质进行了评估。此外，还进行了体外实验，以证实移植对细胞反应的长期影响。总之，我们能够展示不同的降解场景，从而能够研究降解环境对功能化PCL降解模式和速率的影响。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号