...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of Neurophysiology >Long-lasting changes in muscle activation and step cycle variables induced by repetitive sensory stimulation to discrete areas of the foot sole during walking.
【24h】

Long-lasting changes in muscle activation and step cycle variables induced by repetitive sensory stimulation to discrete areas of the foot sole during walking.

机译：肌肉激活的长期变化和通过重复感应刺激对脚底的离散区域进行的重复感应刺激引起的阶梯循环变量。

获取原文
获取原文并翻译 | 示例
   

获取外文期刊封面封底 >>

       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

We examined whether repetitive electrical stimulation to discrete foot sole regions that are phase-locked to the step cycle modulates activity patterns of ankle muscles and induces neuronal adaptation during human walking. Nonnoxious repetitive foot sole stimulation (STIM; 67 pulses at 333?Hz) was given to the medial forefoot (f-M) or heel (HL) regions at 1 ) the stance-to-swing transition, 2 ) swing-to-stance transition, or 3 ) midstance, during every step cycle for 10?min. Stance, but not swing, durations were prolonged with f-M STIM delivered at stance-to-swing transition, and these changes remained for up to 20-30?min after the intervention. Electromyographic (EMG) burst durations and amplitudes in the ankle extensors were also prolonged and persisted for 20?min after the intervention. Interestingly, STIM to HL was ineffective at inducing modulation, suggesting stimulation location-specific adaptation. In contrast, STIM to HL (but not f-M), at the swing-to-stance phase transition, shortened the step cycle by premature termination of swing. Furthermore, the onset of EMG bursts in the ankle extensors appeared earlier than in the control condition. STIM delivered during the midstance phase was ineffective at modulating the step cycle, highlighting phase-dependent adaptation. These effects were absent when STIM was applied while mimicking static postures for each walking phase during standing. Our findings suggest that the combination of walking-related neuronal activity with repetitive sensory inputs from the foot can generate short-term adaptation that is phase-dependent and localized to the site of STIM. NEW & NOTEWORTHY Repetitive (～10 min) long (200 ms) trains of sensory stimulation to discrete areas of the foot sole produce persistent changes in muscle activity and cycle timing during walking. Interactions between the delivery phase and stimulus location determine the expression of the adaptations. These observations bear striking similarities to those in decerebrate cat experiments and may be usefully translated to improving locomotor function after neurotrauma.
机译：我们研究了在人类行走过程中，对与步进周期相锁定的离散脚底区域进行重复电刺激是否会调节脚踝肌肉的活动模式，并诱导神经元适应。在每一步循环中，在1）从站姿到摆动过渡，2）从摆动到站姿过渡，或3）从中间到站姿过渡时，对内侧前脚（f-M）或脚跟（HL）区域进行非伤害性重复足底刺激（STIM；333？Hz的67个脉冲），持续10？在从站姿到挥杆的转换过程中，f-M刺激可以延长最小站姿（而不是挥杆）的持续时间，这些变化持续了20-30天？干预后的分钟。踝关节伸肌的肌电图（EMG）爆发持续时间和振幅也延长并持续20？干预后的分钟。有趣的是，对HL的刺激在诱导调节方面无效，表明刺激位置特异性适应。相比之下，在从挥杆到站姿的过渡阶段，STIM到HL（而不是f-M）通过提前终止挥杆缩短了步进周期。此外，与对照组相比，踝关节伸肌的肌电图爆发出现得更早。在中间阶段提供的刺激在调节步进周期方面无效，突出了相位依赖性适应。当在站立时模拟每个行走阶段的静态姿势时，应用STIM时，这些效应不存在。我们的研究结果表明，行走相关的神经元活动与来自足部的重复性感觉输入相结合，可以产生短暂的适应性，这种适应性是阶段依赖的，并且局限于STIM部位。在步行过程中，对脚底离散区域进行新的、值得注意的（～10分钟）长（200毫秒）的重复感官刺激，会持续改变肌肉活动和循环时间。传递阶段和刺激位置之间的相互作用决定了适应性的表达。这些观察结果与去脑猫实验中的观察结果有着惊人的相似性，可以有效地转化为改善神经营养不良后的运动功能。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号