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首页> 外文期刊>Journal of Physics, D. Applied Physics: A Europhysics Journal >Bulk plasmon polariton based structured illumination microscopy by utilizing hyperbolic metamaterials
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Bulk plasmon polariton based structured illumination microscopy by utilizing hyperbolic metamaterials

机译：基于批量等离子体基于结构化照明显微镜，利用双曲形超材料

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摘要

Because structured illumination microscopy (SIM) has the advantages of wide-field, rapid imaging, and biocompatibility, it is widely used for super-resolution imaging of living cells. Here, we demonstrate a new super-resolution imaging method-bulk plasmon polariton based SIM (BPPSIM), which combines the SIM with the hyperbolic metamaterials (HMMs). By utilizing an HMM composed of a multilayer metal/dielectric film, a deep subwavelength bulk plasmon polariton is obtained. The imaging resolution of BPPSIM can be improved by the uniform and wide-field structured illumination pattern with high spatial frequency, benefiting from the filtering effect of HMM for the spatial frequency spectrum. The resolution of the recovered images by BPPSIM has been increased to 1/8 of the fluorescence wavelength, which is 2.7-fold enhancement in resolution compared with traditional fluorescence microscopy. This proposed approach demonstrates the operability and flexibility of the structured illumination pattern and can be used in a simple, wide-field and super-resolution fluorescence microscope.
机译：由于结构照明显微镜（SIM）具有视场宽、成像速度快、生物相容性好等优点，被广泛用于活体细胞的超分辨率成像。在这里，我们展示了一种新的超分辨率成像方法——基于体等离子体激元的SIM（BPPSIM），它将SIM与双曲超材料（HMM）结合起来。利用多层金属/介质膜构成的HMM，获得了深亚波长体等离子体激元。利用隐马尔可夫模型（HMM）对空间频谱的滤波作用，采用高空间频率的均匀宽视场结构光照模式，可以提高BPPSIM的成像分辨率。BPPSIM恢复图像的分辨率已提高到荧光波长的1/8，与传统荧光显微镜相比，分辨率提高了2.7倍。该方法展示了结构化照明模式的可操作性和灵活性，可用于简单、宽视场和超分辨率荧光显微镜。

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  • 作者

    Liu Xiangzhi; Kong Weijie; Wang Changtao; Pu Mingbo; Li Zhenyan; Li Xiong; Ma Xiaoliang; Luo Xiangang;

  • 作者单位

    Chinese Acad Sci Inst Opt &

    Elect State Key Lab Opt Technol Nanofabricat &

    Microeng Chengdu 610209 Peoples R China;

    Chinese Acad Sci Inst Opt &

    Elect State Key Lab Opt Technol Nanofabricat &

    Microeng Chengdu 610209 Peoples R China;

    Chinese Acad Sci Inst Opt &

    Elect State Key Lab Opt Technol Nanofabricat &

    Microeng Chengdu 610209 Peoples R China;

    Chinese Acad Sci Inst Opt &

    Elect State Key Lab Opt Technol Nanofabricat &

    Microeng Chengdu 610209 Peoples R China;

    Chinese Acad Sci Inst Opt &

    Elect State Key Lab Opt Technol Nanofabricat &

    Microeng Chengdu 610209 Peoples R China;

    Chinese Acad Sci Inst Opt &

    Elect State Key Lab Opt Technol Nanofabricat &

    Microeng Chengdu 610209 Peoples R China;

    Chinese Acad Sci Inst Opt &

    Elect State Key Lab Opt Technol Nanofabricat &

    Microeng Chengdu 610209 Peoples R China;

    Chinese Acad Sci Inst Opt &

    Elect State Key Lab Opt Technol Nanofabricat &

    Microeng Chengdu 610209 Peoples R China;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 应用物理学;
  • 关键词

    super-resolution; structured illumination microscopy; hyperbolic metamaterials; bulk plasmon polariton;

    机译：超分辨率;结构化照明显微镜;双曲型超材料;散装等离子体Polariton;

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