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首页> 外文期刊>Journal of Ethnopharmacology: An Interdisciplinary Journal Devoted to Bioscientific Research on Indigenous Drugs >Inhibition of biofilm and quorum sensing-regulated virulence factors in Pseudomonas aeruginosa by Cuphea carthagenensis (Jacq.) J. F. Macbr. Leaf extract: An in vitro study
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Inhibition of biofilm and quorum sensing-regulated virulence factors in Pseudomonas aeruginosa by Cuphea carthagenensis (Jacq.) J. F. Macbr. Leaf extract: An in vitro study

机译:抑制伯爵碳铜绿假单胞菌(JACQ.)铜绿假单胞菌抑制生物膜和群体传感毒力因子(JACQ。)J.F.Macbr。 叶提取物:体外研究

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摘要

Ethnopharmcological relevance: Microbial biofilm formation, a quorum sensing (QS) regulated process, is one of the major causes of nosocomial and chronic infections, foodborne diseases, and associated deaths. Various approaches have been used to eradicate the menace of biofilm. Ethnomedicinal plants as potent antibiofilm agents are gaining a lot of interest in an era where the drug resistance is increasing and the availability of potent antibiotics is no longer promised. In this context, the methanol extract of Cuphea carthagenensis (CCMD), an ethnomedicinal and culinary herb, was evaluated as an antibiofilm and anti-QS agent against Pseudomonas aeruginosa.
机译:民族药理学相关性:微生物生物膜的形成是一个群体感应(QS)调节的过程,是医院感染和慢性感染、食源性疾病以及相关死亡的主要原因之一。人们已经使用各种方法来消除生物膜的威胁。在耐药性不断增加、有效抗生素不再被承诺提供的时代,作为有效抗生物膜剂的民族医学植物正受到人们的广泛关注。在此背景下,民族医学和烹饪草药迦太基铜甲醇提取物(CCMD)被评估为抗铜绿假单胞菌的抗生物膜和抗QS药物。

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