Neutrophilic drug reactions

Coromilas Alexandra J.; Gallitano Stephanie M.

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Neutrophilic drug reactions

机译：中性药物反应

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Neutrophilic drug reactions are unique eruptions that can affect hospitalized patients and share a common pathophysiology with neutrophils as the key mediators of inflammation. They range in clinical presentation from papules and plaques to bullae and erosions to pustules. Although there is some overlap in presentation, each has distinguishing features that aid the clinician in differentiation from one another and from other drug hypersensitivity reactions. Much of the data on these reactions are from case reports and series or retrospective review studies. There are limited prospective observational studies dedicated to these adverse drug reactions. We review the more common and life-threatening neutruphilic drug reactions, their proposed mechanism of action, and their management. (C) 2020 Elsevier Inc. All rights reserved.

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《Clinics in dermatology》 |2020年第6期|共12页
作者
Coromilas Alexandra J.; Gallitano Stephanie M.;
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Columbia Univ Med Ctr Dept Dermatol New York NY 10027 USA;

Columbia Univ Med Ctr Dept Dermatol New York NY 10027 USA;

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正文语种 eng
中图分类皮肤病学与性病学;
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Neutrophilic drug reactions

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